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Merck
CN

A8378

Sigma-Aldrich

DL-2-烯丙基甘氨酸

别名:

(±)-2-氨基-4-戊烯酸, DL-C-烯丙基甘氨酸

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About This Item

线性分子式:
H2C=CHCH2CH(NH2)CO2H
CAS号:
分子量:
115.13
Beilstein:
1748645
EC 号:
MDL编号:
UNSPSC代码:
12352200
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

方案

≥98% (TLC)

表单

powder

颜色

white

mp

258-260 °C (lit.)

应用

peptide synthesis

储存温度

−20°C

SMILES字符串

NC(CC=C)C(O)=O

InChI

1S/C5H9NO2/c1-2-3-4(6)5(7)8/h2,4H,1,3,6H2,(H,7,8)

InChI key

WNNNWFKQCKFSDK-UHFFFAOYSA-N

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生化/生理作用

DL-2-Allylglycine is a racemic mixture of L- and D-allylglycine. D-allylglycine is the enantiomer of L-allylglycine, a glutamate decarboxylase (GAD) inhibitor used in GABA research. D-allylglycine may be used as a control supplement versus L-allylglycine in GABA research. D-allylglycine is used in the organic synthesis of cyclic opioid peptide agonists and antagonists.

象形图

Exclamation mark

警示用语:

Warning

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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S Moyanova et al.
Acta physiologica et pharmacologica Bulgarica, 15(1), 47-53 (1989-01-01)
The effect of DL-allylglycine (DL-AG) in two doses (40 and 60 mg/kg i.v.) was studied on cats under acute conditions. DL-AG provoked the appearance of epileptiform EEG patterns either spontaneous or in response to intermittent light stimulation with a frequency
Non-centrosymmetric racemates: space-group frequencies and conformational similarities between crystallographically independent molecules.
Dalhus B, Gorbitz CH.
Acta Physiologica Et Pharmacologica Bulgarica, 56, 715-719 (2000)
D A Kunz et al.
Journal of bacteriology, 148(1), 72-82 (1981-10-01)
Spontaneous mutants which acquired the ability to utilize d-allylglycine (d-2-amino-4-pentenoic acid) and dl-cis-crotylglycine (dl-2-amino-cis-4-hexenoic acid) but not l-allylglycine or dl-trans-crotylglycine could be readily isolated from Pseudomonas putida mt-2 (PaM1). Derivative strains of PaM1 putatively cured of the TOL (pWWO) plasmid
M Bottlaender et al.
European journal of pharmacology, 321(1), 13-17 (1997-02-19)
The influence of decreased endogenous gamma-aminobutyric acid (GABA) concentration on benzodiazepine receptor function was studied in the brain of living baboons. Positron emission tomography and the radiotracer [11C]flumazenil combined with electroencephalography were used to determine the pharmacological properties of two
Tadashi Saigusa et al.
Neuropharmacology, 62(2), 907-913 (2011-10-04)
GABA released from accumbal GABAergic interneurons plays an inhibitory role in the regulation of dopamine efflux through GABA(B) and GABA(A) receptors located on accumbal dopaminergic nerve endings. The cytosolic newly synthesised GABA alters vesicular GABA levels and, accordingly, the amount

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