A8008
5α-雄甾-16-烯-3-酮
synthetic (organic), ≥98% (TLC), pheromone, powder
别名:
16-(5α)雄甾烯-3-酮, 3-酮-5α,16-雄甾烯, 雄烯酮
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关于此项目
经验公式（希尔记法）:
C19H28O
化学文摘社编号:
分子量:
272.43
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
242-220-1
MDL number:
产品名称
5α-雄甾-16-烯-3-酮,
InChI key
HFVMLYAGWXSTQI-QYXZOKGRSA-N
InChI
1S/C19H28O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,13,15-17H,4-8,10-12H2,1-2H3/t13-,15-,16-,17-,18-,19-/m0/s1
SMILES string
[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)C=CC[C@@]34[H])[C@@]1(C)CCC(=O)C2
biological source
synthetic (organic)
assay
≥98% (TLC)
form
powder
mp
140-145 °C (lit.)
solubility
dichloromethane: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
Quality Level
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相关类别
Application
5α-Androst-16-en-3-one has been used:
- to quantify its concentration in various fat tissues
- to study its trigeminal percept and implications on the rate of specific anosmia
- to study the effects of immunocastration on meat quality and sensory properties of pork bellies
General description
5α-Androst-16-en-3-one (androstenone) is a mammalian pheromone found in boar saliva, human sweat, and human urine.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Gang Chen et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(1), 56-60 (2007-10-03)
CYP2A6 is one of the enzymes involved in the hepatic metabolism of a naturally produced compound, skatole, in the pig. Low CYP2A6 activity has been linked to excessive accumulation of skatole in pig adipose tissue and development of the phenomenon
The scents of androstenone in humans.
Ricardo C Araneda et al.
The Journal of physiology, 554(Pt 1), 1-1 (2003-12-18)
Jochen Fischer et al.
Analytical chemistry, 83(17), 6785-6791 (2011-08-02)
The steroidal pig pheromones androstenone (5α-androst-16-en-3-one), 3α-androstenol (5α-androst-16-en-3α-ol), and 3β-androstenol (5α-androst-16-en-3β-ol) as well as the heterocyclic aromatic amines skatole and indole, originating from microbial degradation of tryptophan in the intestine of pigs, are frequently recognized as the major compounds responsible
P A Sinclair et al.
Journal of animal science, 83(2), 358-365 (2005-01-13)
This study examined the relationship between sulfoconjugation and the degree to which 5alpha-androstenone can accumulate in fat. Analysis of the unconjugated and sulfoconjugated fractions of peripheral plasma from 25 mature Yorkshire boars and testicular vein plasma from an additional 20
G Zamaratskaia et al.
Reproduction in domestic animals = Zuchthygiene, 39(3), 168-172 (2004-06-09)
This study describes the age-related variation in boar taint compounds, skatole and androstenone, and testosterone, oestradiol-17 beta (E17 beta), oestrone sulphate (ES), dehydroepiandrosterone sulphate (DHEAS), triiodothyronine (T(3)) and insulin-like growth factor-1 (IGF-1) in six boars. Three pairs of littermates of
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