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Merck
CN

A7883

Sigma-Aldrich

5α-雄甾-16-烯-3α-醇

别名:

16-(5α)雄甾烯-3α-醇, 3α-羟基-5α-雄甾-16-烯

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About This Item

经验公式(希尔记法):
C19H30O
CAS号:
分子量:
274.44
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic (organic)

质量水平

检测方案

≥98% (TLC)

形式

powder

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

技术

GC/MS: suitable

mp

140-141 °C (lit.)

溶解性

ethanol: 19.60-20.40 mg/mL, clear, colorless

运输

ambient

储存温度

room temp

SMILES字符串

C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@]34C)[C@@H]1CC=C2

InChI

1S/C19H30O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,13-17,20H,4-8,10-12H2,1-2H3/t13-,14+,15-,16-,17-,18-,19-/m0/s1

InChI key

KRVXMNNRSSQZJP-PHFHYRSDSA-N

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应用

5-α-androst-16-en-3-α-ol (androstenol) is an androgen believed to act as a pheromone. Androstenol has been used in a study to develop a combined gas chromatography/thermal conversion/isotope ratio mass spectrometry (GC/TC/IRMS) method for D/H ratio determination of endogenous urinary steroids.

生化/生理作用

5alpha-androst-16-en-3alpha-ol (androstenol), is an androgen believed to act as a pheromone.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Jeremy Vincent et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 61(Pt 1), 156-159 (2006-03-02)
The constitutive androstane receptor (CAR) is a member of the nuclear receptor superfamily. In contrast to classical nuclear receptors, which possess small-molecule ligand-inducible activity, CAR exhibits constitutive transcriptional activity in the apparent absence of ligand. CAR is among the most
Guan Wang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 870(2), 209-215 (2008-07-01)
A novel method using solid-phase extraction coupled with gas chromatography and flame ionization detector (FID)/electron impact mass spectrometry (EIMS) was developed for the determination of 5alpha-androst-16-en-3alpha-ol (androstenol), a steroidal compound belonging to the group of musk odorous 16-androstenes, in truffle
S Stefańczyk-Krzymowska et al.
Experimental physiology, 85(6), 801-809 (2001-02-24)
It is generally accepted that pheromones act by stimulating of the dendritic receptors of the olfactory neurones massed in the olfactory epithelium. This study was designed to ascertain whether it is possible for the boar pheromone androstenol (5alpha-androst-16-en-3-ol) to be
Thomas Piper et al.
Rapid communications in mass spectrometry : RCM, 23(13), 1917-1926 (2009-05-23)
The development and application of a combined gas chromatography/thermal conversion/isotope ratio mass spectrometry (GC/TC/IRMS) method for D/H ratio determination of endogenous urinary steroids are presented. The key element in sample preparation was the consecutive cleanup with high-performance liquid chromatography of
W D Booth
Journal of reproduction and fertility, 81(2), 427-431 (1987-11-01)
The pheromone binding protein 'pheromaxein' which binds the pheromonal 16-androstene steroids in the saliva of the male pig (boar), was degraded and lost its binding activity in saliva incubated in air for 72 h at 21 degrees C and 37

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