检测方案
≥98% (TLC)
质量水平
形式
powder
药品控制
USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
技术
toxicology assay: suitable
溶解性
methanol: 19.60-20.40 mg/mL, clear, colorless
储存温度
room temp
SMILES字符串
[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI
1S/C19H32O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-17,20-21H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,17-,18-,19-/m0/s1
InChI key
CBMYJHIOYJEBSB-KHOSGYARSA-N
基因信息
rat ... Ar(24208)
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应用
5α-Androstane-3α,17β-diol (dihydroandrosterone) is a testosterone metabolite. Dihyroandrosterone inhibited the cell growth of seven cancer cell lines while showing weak toxicity on normal cell lines.
生化/生理作用
Dihydroandrosterone is a testosterone metabolite; affects sperm maturation and survival.
警示用语：
Danger
危险声明
预防措施声明
危险分类
Carc. 2 - Repr. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
D H Garnier et al.
General and comparative endocrinology, 116(2), 281-290 (1999-11-24)
Concentrations of testosterone, progesterone, Delta4-androstenedione, dihydrotestosterone, 11-ketotestosterone, estrone, estradiol-17beta, 5alpha-androstane, 3alpha, 17beta-diol, and 17alpha-hydroxy, 20beta-dihydroprogesterone were determined by radioimmunoassays in the blood plasma and testicular homogenates of Scyliorhinus canicula. Samples were collected almost every month for 27 months. The weights
Cheryl A Frye
Pharmacology, biochemistry, and behavior, 86(2), 354-367 (2006-11-23)
The abuse of anabolic-androgenic steroids (AS) is a growing problem; however, the effects and mechanisms underlying their addictive effects are not well understood. Research findings regarding androgen abuse in people and hedonic effects of androgens in laboratory rats are reviewed.
17α-ethynyl-5α-androstane-3α, 17β-diol treatment of MNU-induced mammary cancer in rats
Ahlem, C., et al.
International Journal of Breast Cancer, doi: 10-doi: 10 (2011)
R S Rittmaster et al.
The Journal of clinical endocrinology and metabolism, 76(4), 977-982 (1993-04-01)
Androstanediol glucuronide (Adiol G) has been reported to be a marker of peripheral androgen metabolism and action. It consists of two isomers, Adiol 3-G and Adiol 17-G. Adiol G is formed from unconjugated precursors by the enzyme glucuronyl transferase. To
B Eckstein et al.
Biochimica et biophysica acta, 627(2), 165-171 (1980-01-17)
Serum testosterone levels are elevated prior to the lutropin surge, and decline abruptly following the release of endogenous lutropin. To investigate this phenomenon, the activity of 17 beta-hydroxysteroid dehydrogenase, the enzyme directly related to testosterone production from androstenedione, was measured.
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