A7505
1,4-Androstadiene-3,17-dione
别名:
1-Dehydroandrostenedione, Androstadienedione
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关于此项目
经验公式（希尔记法）:
C19H24O2
化学文摘社编号:
分子量:
284.39
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
212-977-2
MDL number:
biological source
synthetic (organic)
Quality Level
assay
≥85% (HPLC)
form
powder
drug control
USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility
chloroform: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
room temp
SMILES string
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]
InChI
1S/C19H24O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-16H,3-6,8,10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
InChI key
LUJVUUWNAPIQQI-QAGGRKNESA-N
Gene Information
human ... CYP19A1(1588)
General description
1,4-Androstadiene-3,17-dione is a 17-keto anabolic steroid.
Biochem/physiol Actions
1,4-Androstadiene-3,17-dione is a prohormone that converts to an active steroid through the 17bHSD enzyme. 1,4-Androstadiene-3,17-dione is a metabolite of progesterone.
1,4-Androstadiene-3,17-dione is useful in forming pharmaceutically important steroids. Regio- and stereospecific hydroxylation of 1,4-androstadiene-3,17-dione increases its biological activity. Its derivative is also used to produce high-value bile acids. 1,4-Androstadiene-3,17-dione serves as a precursor for the synthesis of progesterone, testosterone, cortisol, estradiol, cortisone, prednisolone, and prednisone.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Carc. 2 - Lact. - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
兴奋剂蛋白同化制剂
此项目有
Rosa M Lopparelli et al.
Steroids, 76(5), 508-516 (2011-02-08)
Recently, the effect of illicit growth promoters (GPs) upon the cattle transcriptome has drawn the increasing attention of the scientific community. In the present study, the pre-transcriptional effects of three different illicit protocols on a set of target genes, including
Rosa Draisci et al.
Proteomics, 7(17), 3184-3193 (2007-08-07)
Surveillance of illegal use of steroids hormones in cattle breeding is a key issue to preserve human health. To this purpose, an integrated approach has been developed for the analysis of plasma and urine from calves treated orally with a
Francesca T Cannizzo et al.
The Journal of veterinary medical science, 69(11), 1109-1116 (2007-12-07)
Boldenone and its precursor Boldione are illegally used for anabolic purposes in humans, horses and cattle. To develop more effective policies and programs to maximize food security, Italian Public Health Services investigate all indicators capable of assisting the recognition of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A7505-5G | 04061832847597 |
| A7505-1G | 04061826232408 |