所有图片(1)
About This Item
经验公式（希尔记法）:
C22H36O3
CAS号:
分子量:
348.52
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
表单
powder
质量水平
储存条件
protect from light
颜色
white to beige
溶解性
DMSO: ≥20 mg/mL
储存温度
−20°C
SMILES字符串
CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O
InChI
1S/C22H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h15,17-18,23H,2-14,16H2,1H3,(H,24,25)
InChI key
ADFWQBGTDJIESE-UHFFFAOYSA-N
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应用
漆树酸已：
- 用作组蛋白乙酰化酶(HAT)抑制剂，以研究其对大鼠皮层神经元的影响
- 用作体外乙酰化试验的阳性对照
- 用作乙酰化酶抑制剂，以研究其对转染人胚胎肾细胞的核糖核酸输出1 (Rae-1)蛋白乙酰化的影响
生化/生理作用
漆树酸是一种从腰果果壳中提取的天然生物活性化合物。它具有抗真菌、抗菌、抗白蚁和杀软体动物的活性。漆树酸作为一种治疗剂，可对抗肥胖、癌症、炎症疾病和氧化损伤。它作为各种酶的抑制剂，如脂氧合酶(LOX-1)、黄嘌呤氧化酶、核因子κ B (NFκB)激酶、酪氨酸酶和脲酶。
漆树酸是 HAT（组蛋白乙酰转移酶）抑制剂。
特点和优势
这种化合物是基因调控研究的特色产品。点击此处发现更多特色基因调控产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Mingxi Li et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(30), 3885-3892 (2009-10-16)
Global histone modifications and their putative relevance to short and long term cellular programming have drawn substantial interest in the study of chromatin. Here we describe the use of reverse-phase liquid chromatography coupled to Linear Ion Trap-Fourier Transform Mass Spectrometry
Mahadevappa Hemshekhar et al.
Basic & clinical pharmacology & toxicology, 110(2), 122-132 (2011-11-23)
Anacardic acid (AA) is a bioactive phytochemical found in nutshell of Anacardium occidentale. Chemically, it is a mixture of several closely related organic compounds, each consisting of salicylic acid substituted with an alkyl chain. The traditional Ayurveda depicts nutshell oil
B Devipriya et al.
Journal of molecular graphics & modelling, 34, 57-66 (2012-02-07)
A charge density analysis has been performed on gas phase and docked forms of anacardic acid molecule to understand its charge density distribution, electrostatic moments and the conformation in the active site of p300 enzyme. Here, we report the binding
Ishwariya Venkatesh et al.
Neuroepigenetics, 8, 19-26 (2016-12-19)
Axon regeneration in adult central nervous system (CNS) is limited in part by a developmental decline in the ability of injured neurons to re-express needed regeneration associated genes (RAGs). Adult CNS neurons may lack appropriate pro-regenerative transcription factors, or may
ZhenHua Ni et al.
Respiratory research, 12, 47-47 (2011-04-15)
"Phosphatase and tensin homolog deleted on chromosome 10" (PTEN) is mostly considered to be a cancer-related gene, and has been suggested to be a new pathway of pathogenesis of asthma. The purpose of this study was to investigate the effects
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