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文件

安全信息

A7223

Sigma-Aldrich

白蛋白 人

recombinant, expressed in Pichia pastoris, 5% in aqueous buffer, ≥90% (SDS-PAGE)

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别名:
Albagen™, rHSA
经验公式（希尔记法）:
C2936H4624N786O889S41
CAS号:
70024-90-7
分子量:
66471.53
MDL编号:
MFCD00081418
UNSPSC代码:
12352202
NACRES:
NA.25

生物来源

human

质量水平

200

重组

expressed in Pichia pastoris

检测方案

≥90% (SDS-PAGE)

形式

solution

分子量

monomer ~67 kDa

浓度

5% in aqueous buffer

技术

cell culture | mammalian: suitable

UniProt登记号

P02768

运输

wet ice

储存温度

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

基因信息

human ... ALB(213)

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相关类别

应用

该重组变异建议用于：吸收、分散、代谢和排泄（ADME）药理学研究；细胞培养；药物递送研究；细胞冻存。

生化/生理作用

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

物理属性

Asp N末端缺失的重组构建体。X射线晶体学证实了其与天然白蛋白的结构等同性。Asp N末端是主要的Cu2+和Ni2+ 螯合位点；其缺失消除了一个重要的抗原决定簇，让蛋白质具有低过敏源性。还可在Cys34处阻断，改善稳定性、单体含量和均质性。

外形

磷酸盐缓冲盐水溶液，含有4 mM辛酸钠和 4 mM N-乙酰色氨酸。

其他说明

更多信息参见人血清白蛋白。

法律信息

Albagen is a trademark of Albumin Therapeutics, LLC.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the concentration of Product A7223, Albumin human - recombinant?

    The concentration of this solution is 50 mg/mL.

  4. How many milliliters are in the 1 gram package size of Product A7223, Albumin human - recombinant?

    There are 20 mL of albumin solution in the 1 gram package size.

  5. What is the molecular mass of the recombinant albumin used in preparing Product A7223, Albumin human - recombinant?

    This recombinant protein contains 584 amino acid residues (66,357 Dalton) derived from the prototypical human serum albumin sequence, Gene Bank Accession No. M12523, with a single deletion of the N-terminal residue (Asp).  The N-terminal deletion of the Asp reduces the affinity by which nickel and copper bind to the protein.  Otherwise, the biological properties are identical as for the full-length protein.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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