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Merck
CN

A7003

Sigma-Aldrich

海藻酸 来源于褐藻

powder

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别名:
海藻酸 来源于巨藻, 甘露糖醛酸和古罗糖醛酸的混合聚合物
线性分子式:
(C6H8O6)n
CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12171500
NACRES:
NA.47

形式

powder

质量水平

颜色

white to light yellow

pH值范围

1.5-3.5

mp

300 °C

溶解性

H2O: insoluble, but swells
aqueous base: soluble

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

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一般描述

海藻酸是从海藻中分离出的高分子量线性聚合物。它是 n-甘露糖醛酸和L-古罗糖醛酸的线性β-1→4-连接聚合物。它是存在于褐藻细胞外基质中的酸性多糖。据报道,它可以抑制HIV的逆转录酶活性。海藻酸的结构研究表明它是一种海藻多糖聚-α-L-古罗糖醛酸。已有报道称,从褐藻( Sargassum wightii)中分离的海藻酸在II型胶原蛋白诱导的关节炎大鼠中具有抗炎作用。已有报道称,利用py-GC/MS在宽温度范围(200-800℃)内以及热重分析(TGA)研究了藻酸的热解。据报道,它能够在锗内反射元件(IRE)上引起铜薄膜的生物腐蚀。

应用

海藻酸试剂适用于研究藻酸盐的 体外体内 促有丝分裂活性。它适用于通过染料结合试验对透明胞外聚合物颗粒进行分光光度测定。

其他说明

一种直链、亲水、胶体状聚糖醛酸,主要由具有1→4键的脱水-β-D-甘露糖醛酸残基组成。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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C H Sarithakumari et al.
International immunopharmacology, 17(4), 1108-1115 (2014-01-22)
The present study evaluated the anti-inflammatory potential of alginic acid isolated from the brown algae Sargassum wightii in type II collagen induced arthritic rats, a well established arthritic model that resembles more closely to human rheumatoid arthritis in its clinical
Structural components of alginic acid. II. The crystalline structure of poly-alpha-L-guluronic acid. Results of x-ray diffraction and polarized infrared studies.
E D Atkins et al.
Biopolymers, 12(8), 1879-1887 (1973-01-01)
Ramón Rial et al.
Nanomaterials (Basel, Switzerland), 10(7) (2020-07-09)
Hydrogels exhibit excellent properties that enable them as nanostructured scaffolds for soft tissue engineering. However, single-component hydrogels have significant limitations due to the low versatility of the single component. To achieve this goal, we have designed and characterized different multi-component
K C S Queiroz et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 62(5), 303-307 (2008-05-06)
Brown algae have two kinds of acid polysaccharides present in the extracellular matrix: sulfated fucan and alginic acid. We have previously isolated and characterized fucans from several species of brown seaweed. The characterized fucans from Dictyotaceae are heterofucans containing mainly
G Klöck et al.
Applied microbiology and biotechnology, 40(5), 638-643 (1994-01-01)
Alginate is used as a matrix for immunoisolation of cells and tissues in vivo. We have demonstrated previously that commercial alginates contain various fractions of mitogenic impurities and that they can be removed by free flow electrophoresis. The use of

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