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Merck
CN

A6950

Sigma-Aldrich

Acetyl-Lys-D-Ala-D-Ala

≥95% (HPLC)

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经验公式(希尔记法):
C14H26N4O5
CAS号:
分子量:
330.38
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥95% (HPLC)

形式

powder

溶解性

water: 10 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

CC(NC(=O)C(C)NC(=O)C(CCCCN)NC(C)=O)C(O)=O

InChI

1S/C14H26N4O5/c1-8(12(20)17-9(2)14(22)23)16-13(21)11(18-10(3)19)6-4-5-7-15/h8-9,11H,4-7,15H2,1-3H3,(H,16,21)(H,17,20)(H,18,19)(H,22,23)

InChI key

GMSXMADYKTYBCP-UHFFFAOYSA-N

相关类别

底物

Substrate for carboxypeptidase G and DD from Streptomyces albus.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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P Groves et al.
Structure (London, England : 1993), 2(8), 747-754 (1994-08-15)
Glycopeptide antibiotics of the vancomycin group are of crucial clinical importance in the treatment of methicillin resistant Staphylococcus aureus (MRSA)--the often lethal 'super-bug'--characterized by its resistance to a wide range of antibiotics in common use. The antibiotics exert their physiological
D H Williams et al.
Science (New York, N.Y.), 280(5364), 711-714 (1998-05-23)
The cooperativity between binding of cell wall precursor analogs (ligands) to and antibiotic dimerization of the clinically important vancomycin group antibiotics was investigated by nuclear magnetic resonance. When dimerization was weak in the absence of a ligand, the increase in
L Varetto et al.
European journal of biochemistry, 162(3), 525-531 (1987-02-02)
Titration of the active-site serine DD-peptidase of Streptomyces R61 shows that formation of acyl enzyme during hydrolysis of the substrate Ac2-L-Lys-D-Ala-D-Ala and enzyme inactivation by the beta-lactam compounds benzylpenicillin, N-acetylampicillin and ampicillin relies on the acidic form of an enzyme's
Eric C DiBiasio et al.
Journal of bacteriology, 202(20) (2020-08-12)
Uropathogenic Escherichia coli (UPEC) is the leading cause of human urinary tract infections (UTIs), and many patients experience recurrent infection after successful antibiotic treatment. The source of recurrent infections may be persistent bacterial reservoirs in vivo that are in a

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