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Merck
CN

A6661

白蛋白,二硝基苯

lyophilized powder

别名:

DNP-白蛋白 人

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
Biological source:
human
Form:
lyophilized powder
Technique(s):
RNA extraction: suitable
Impurities:
Infectious agents, tested
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SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

biological source

human

form

lyophilized powder

extent of labeling

30-40 mol DNP per mol albumin

technique(s)

RNA extraction: suitable

impurities

Infectious agents, tested

UniProt accession no.

storage temp.

2-8°C

Quality Level

Gene Information

human ... ALB(213)

Application

用于免疫分析中的检测。可以用作通过IgE受体激活嗜碱性粒细胞的免疫学攻击。
白蛋白,二硝基苯已被用来评估大鼠肥大细胞的脱颗粒作用:
  • 蜂斗菜内酯B
  • 4-羟基-2-(4-羟苯基)异吲哚啉酮-1,3-二酮(PD1)
  • 米非司酮

Analysis Note

源材料的HIV和HBsAg检测结果为阴性

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

高风险级别生物产品--人源产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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B Jabril-Cuenod et al.
The Journal of biological chemistry, 271(27), 16268-16272 (1996-07-05)
Antigen receptors on T- and B-cells activate Ras through a signaling pathway that results in the tyrosine phosphorylation of Shc and the formation of a complex of Shc with the Grb2 adaptor protein. The high affinity receptor for immunoglobulin E
Xuan Che et al.
International journal of medical sciences, 17(2), 224-233 (2020-02-11)
Background: Adenomyosis is a quite common gynecological disorder and above 30% of patients have typical secondary and progressive dysmenorrhea. Current treatments still have many disadvantages and thereby the novel treatment aiming to relieve dysmenorrhea still needs to be further investigated.
Carolin N Zorn et al.
Scientific reports, 8(1), 15467-15467 (2018-10-21)
Antigen (Ag)-mediated crosslinking of IgE-loaded high-affinity receptors for IgE (FcεRI) on mast cells (MCs) triggers activation of proinflammatory effector functions relevant for IgE-associated allergic disorders. The cytosolic tyrosine kinase BTK and the SH2-containing inositol-5'-phosphatase SHIP1 are central positive and negative
Julien Stackowicz et al.
The Journal of experimental medicine, 218(10) (2021-09-04)
Gain-of-function mutations in NLRP3 are responsible for a spectrum of autoinflammatory diseases collectively referred to as "cryopyrin-associated periodic syndromes" (CAPS). Treatment of CAPS patients with IL-1-targeted therapies is effective, confirming a central pathogenic role for IL-1β. However, the specific myeloid
G J Heywood et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 51(4), 176-181 (2002-06-13)
Nicorandil is a potassium channel opener and nitric oxide (NO) donor, and the hypothesis was tested that these modes of action may inhibit cellular degranulation and release of tumour necrosis factor-alpha (TNF-alpha). TNF-alpha and beta-hexosaminidase secretion were measured from rat

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