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主要文件

安全信息

A6655

Sigma-Aldrich

Aflatoxin B₁−BSA Conjugate

from Aspergillus flavus, powder, hepatotoxic mycotoxin

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About This Item

MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.77

产品名称

黄曲霉毒素B1−BSA共轭物 来源于黄曲霉,

表单

powder

质量水平

标记范围

8-12 mol Aflatoxin B1 per mol BSA

储存温度

2-8°C

一般描述

Aflatoxin B1 is the most toxic aflatoxin. Aflatoxins are hepatotoxic metabolites, that are produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins contaminate human food and animal feed. They are linked to liver cancer, immune system suppression, reduced growth rates, losses in feed efficiency and death. They are naturally found toxic carcinogens and the most widely known mycotoxins. They mainly contaminate fruits, vegetables and grains.

应用

Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene.
Aflatoxin B1-BSA Conjugate from Aspergillus flavus has been used in immunization of mice with phage and synthetic peptide. It is also used as a target molecule in si field-effect transistor (FET) biosensing techniques.

警告

可能致癌。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
Physicochemical and immunological characterization of chitosan-coated bacteriophage nanoparticles for in vivo mycotoxin modeling
de Andrade CYT, et al.
Carbohydrate Polymers, 185(4), 63-72 (2018)
Detection of uncharged or feebly charged small molecules by field-effect transistor biosensors
Ah CS, et al.
Biosensors And Bioelectronics, 33(1), 233-240 (2012)
Morvarid Karamkhani et al.
Environmental monitoring and assessment, 192(7), 472-472 (2020-07-02)
Many workers are exposed to health problems arising from molds, fungi, and their toxins during waste processing. Aflatoxin B1 (AFB1) level in airborne and settled dust, aflatoxin B1-albumin (AFB1-Alb) adduct in serum, liver and kidney biochemical tests, and body redox
P Sizaret et al.
Journal of immunological methods, 63(2), 159-162 (1983-10-14)
We reported previously on the properties of an anti-aflatoxin B1 (AFB) antiserum raised with a conjugate in which AFB is coupled at the C8 position to bovine serum albumin (BSA). The hapten/carrier protein molar ratio of the conjugate was 14.

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