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安全信息

A6636

Sigma-Aldrich

黄曲霉毒素B1 来源于黄曲霉

greener alternative

from Aspergillus flavus

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经验公式（希尔记法）:
C17H12O6
CAS号:
1162-65-8
分子量:
312.27
Beilstein:
1269174
EC 号:
214-603-3
MDL编号:
MFCD00869647
UNSPSC代码:
12352200
PubChem化学物质编号:
24891116
NACRES:
NA.77

生物来源

Aspergillus flavus

质量水平

300

检测方案

≥98.0% (HPLC)

形式

powder

环保替代产品得分

old score: 51
new score: 42
Find out more about DOZN™ Scoring

环保替代产品特性

Waste Prevention
Designing Safer Chemicals
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

环保替代产品分类

Re-engineered,

储存温度

2-8°C

SMILES字符串

COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCC5=O)c14

InChI

1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1

InChI key

OQIQSTLJSLGHID-WNWIJWBNSA-N

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一般描述

我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别，在“预防废弃物”、“设计更安全的化学品和产品”和“节能设计”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

应用

黄曲霉毒素 B1 是一种致癌化合物，在 p53 抑癌基因的 249 位密码子处诱导 G 转化为 T。 在检测食品中的黄曲霉毒素污染时，黄曲霉毒素 B1 可用作内标。

生化/生理作用

黄曲霉毒素 B1 是由黄曲霉（一种常见的土壤真菌）产生的致癌化合物，在 p53 抑癌基因第 249 位密码子处可诱导 G 转化为 T。黄曲霉毒素 B1 是食品污染物和肝致癌物。黄曲霉毒素通过 P450 I 期酶（主要是 CYP3A4）经黄曲霉毒素 B1 3-羟基化反应生物转化为遗传毒性中间体。排毒取决于 II 期酶，例如谷胱甘肽 S-转移酶和 AFB（1）-醛还原酶（AFAR）。黄曲霉毒素 B1 是 CYP1A2、CYP2A6、CYP2D6 和 CYP3A 家族的底物。

警告

可能致癌.

标准

产品编号
说明
价格

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Carc. 1B - Muta. 1B - Repr. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

高风险级别生物产品--毒素类产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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