所有图片(1)
About This Item
经验公式（希尔记法）:
C2936H4624N786O889S41
CAS号:
分子量:
66471.53
EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.25
推荐产品
生物来源
human
重组
expressed in rice
方案
≥99% (PAGE)
表单
lyophilized powder
分子量
monomer ~67 kDa
组成
Protein, ≥90% biuret
技术
cell culture | mammalian: suitable
杂质
≤6.7 EU/g Endotoxin
pH值范围
6.5-7.2
UniProt登记号
储存温度
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
基因信息
human ... ALB(213)
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一般描述
Human serum albumin (HSA) is encoded by the gene mapped to human chromosome 4. Albumin is a globular protein with 585 amino acids. It is the most prominent protein in human sera. Albumin constitutes total concentration of about 60% of the total proteins in the blood serum. The encoded protein contains three globular domains that resemble each other in structure, each containing two subdomains. Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds.
应用
该重组变异建议用于：吸收、分散、代谢和排泄（ADME）药理学研究；细胞培养；药物递送研究；细胞冻存。
生化/生理作用
白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。
Serum albumin functions as a carrier protein for steroids, fatty acids and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood. This globular protein is broadly used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, fetal erythroblastosis and ascites caused by liver cirrhosis. HSA has various biological applications, such as carrier of oxygen, nanodelivery of drugs and fusion of peptides.
其他说明
更多信息参见人血清白蛋白。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Large-scale production of functional human serum albumin from transgenic rice seeds.
He Y, et al.
Proceedings of the National Academy of Sciences of the USA, 201109736-201109736 (2011)
Large-scale production of functional human serum albumin from transgenic rice seeds.
He Y, et al.
Proceedings of the National Academy of Sciences of the USA, 201109736-201109736 (2011)
Hung X Nguyen et al.
Nature communications, 13(1), 620-620 (2022-02-04)
Therapies for cardiac arrhythmias could greatly benefit from approaches to enhance electrical excitability and action potential conduction in the heart by stably overexpressing mammalian voltage-gated sodium channels. However, the large size of these channels precludes their incorporation into therapeutic viral
The three recombinant domains of human serum albumin structural characterization and ligand binding properties.
Dockal M, et al.
The Journal of Biological Chemistry, 274(41), 29303-29310 (1999)
Ilya Y Shadrin et al.
Nature communications, 8(1), 1825-1825 (2017-12-01)
Despite increased use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) for drug development and disease modeling studies, methods to generate large, functional heart tissues for human therapy are lacking. Here we present a "Cardiopatch" platform for 3D culture and
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