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Merck
CN

A6602

Sigma-Aldrich

Anti-ADAMTS-3, Propeptide Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

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别名:
Anti-A Disintegrin And Metalloproteinase with ThromboSpondin-3 motif
MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous glycerol solution

种属反应性

human

浓度

~1 mg/mL

技术

western blot: 1:1,000

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... ADAMTS3(9508)

一般描述

ADAMTS-3 belongs to the ADAM (A Disintegrin And Metalloproteinase) family and has thrombospondin (TS) repeats. Studies have suggested that ADAMTS-3 is preferably expressed in the cartilages and has procollagen II N-propeptidase functions. Rabbit Anti-ADAMTS-3, Propeptide Region antibody binds to propeptide region of human ADAMTS-3.
By immunoblotting against the reduced protein, the antibody identifies the zymogen form at 130-140 kDa, activated forms at 94-105 kDa (major bands), and breakdown products at 50 kDa, 34 kDa in cell culture media and lysates.

免疫原

synthetic peptide corresponding to the propeptide domain of human ADAMTS-3.

应用

Rabbit Anti-ADAMTS-3, Propeptide Region can be used for western blot assays at a dilution of 1:1,000.

外形

Solution in phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

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R J Fernandes et al.
The Journal of biological chemistry, 276(34), 31502-31509 (2001-06-16)
The amino and carboxyl propeptides of procollagens I and II are removed by specific enzymes as a prerequisite for fibril assembly. Null mutations in procollagen I N-propeptidase (ADAMTS-2) cause dermatosparaxis in cattle and the Ehlers-Danlos syndrome (dermatosparactic type) in humans

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