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Merck
CN

A6428

Sigma-Aldrich

黄曲霉毒素M1

from Aspergillus flavus

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About This Item

经验公式(希尔记法):
C17H12O7
CAS号:
分子量:
328.27
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

生物来源

Aspergillus flavus

质量水平

形式

film

储存温度

2-8°C

SMILES字符串

[H][C@]12OC=C[C@@]1(O)c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1

InChI key

MJBWDEQAUQTVKK-IAGOWNOFSA-N

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一般描述

Aflatoxins are metabolites of fungus, that are mainly seen in feeds and foods. Aflatoxin M1 is a hydroxylated metabolite of aflatoxin B1. It is liberated in milk, urine and produced in liver after receiving aflatoxin B1.

应用

Aflatoxin M1 has been used as a standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in Brazilian milk and infant formula. It has also been used as standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in dairy products produced in Brazil.
Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.

生化/生理作用

Aflatoxin M1 possesses hepatocarcinogenic properties.

警告

可能致癌。

制备说明

Aspergillus flavus metabolite.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Carc. 1B - Muta. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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访问文档库

Aflatoxins
Handbook of Secondary Fungal Metabolites, 545-569 (2003)
Nathalie Paniel et al.
Sensors (Basel, Switzerland), 10(10), 9439-9448 (2010-01-01)
We have developed an electrochemical immunosensor for the detection of ultratrace amounts of aflatoxin M(1) (AFM(1)) in food products. The sensor was based on a competitive immunoassay using horseradish peroxidase (HRP) as a tag. Magnetic nanoparticles coated with antibody (anti-AFM(1))
Aflatoxins
Handbook of Secondary Fungal Metabolites (2003)
Aflatoxin M1 in milk and distribution and stability of aflatoxin M1 during production and storage of yoghurt and cheese
Iha MH, et al.
Food Control, 29(1), 1-6 (2013)
Occurrence of aflatoxin M1 in dairy products in Brazil
Iha MH, et al.
Food Control, 22(12), 1971-1974 (2011)

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