所有图片(1)
About This Item
经验公式（希尔记法）:
C19H35N3O4S
CAS号:
分子量:
401.56
Beilstein:
7693643
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
检测方案
≥95% (HPLC)
质量水平
形式
powder
颜色
white
溶解性
ethanol: 20 mg/mL
储存温度
−20°C
SMILES字符串
[H]C(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
InChI
1S/C19H35N3O4S/c1-12(2)9-16(20-14(5)24)19(26)22-17(10-13(3)4)18(25)21-15(11-23)7-8-27-6/h11-13,15-17H,7-10H2,1-6H3,(H,20,24)(H,21,25)(H,22,26)/t15-,16-,17-/m0/s1
InChI key
RJWLAIMXRBDUMH-ULQDDVLXSA-N
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应用
钙蛋白酶抑制剂 II 已用于蛋白质印迹。此外，它还用于研究Spy1A（一类细胞周期蛋白）在细胞周期中的降解机制。
钙蛋白酶抑制剂II是一种细胞透过性肽，可限制钙蛋白酶、组织蛋白酶 L 和组织蛋白酶 B 的活性。钙蛋白酶抑制剂 II 还可以防止甲基汞诱导的大鼠小脑神经元细胞死亡。
生化/生理作用
钙蛋白酶是在神经系统中表达的半胱氨酸蛋白酶。钙蛋白酶表现出钙依赖性酶活性。在小鼠模型中，抑制钙蛋白酶可防止血管紧张素II诱导的白细胞浸润，并减轻血管周围炎症。
其他说明
以前为 CAS# 136632-32-1
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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