推荐产品
生物来源
mouse
质量水平
偶联物
alkaline phosphatase conjugate
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
9E10, monoclonal
表单
buffered aqueous glycerol solution
种属反应性
human
技术
ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: 1:100 using a myc-tagged fusion protein.
同位素/亚型
IgG1
UniProt登记号
储存温度
2-8°C
靶向翻译后修饰
unmodified
基因信息
human ... MYC(4609)
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一般描述
Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-myc gene encodes for a protein of 62kDa called p62c-myc is associated mainly with cell nuclei.
免疫原
人p62c-Myc蛋白的合成肽。
应用
Anti-c-Myc-Alkaline Phosphatase antibody has been used in
- enzyme linked immunosorbent assay (ELISA)
- immunohistochemical labeling
- immunostaining
- western blotting
Monoclonal Anti-c-Myc-Alkaline Phosphatase antibody can be used for western blot assays at 1:100, using myc-tagged fusion proteins. The antibody can also be used for immunohistochemical applications.
生化/生理作用
The c-myc oncogene product(p62c-myc) exerts normal and oncogenic cellular functions. Elevated level of c-myc protein in malignant tissues when compared with normal tissue, but with the unexpected finding of a cytoplasmic accumulation of the protein in these tumors.
外形
Solution in 0.05 M Tris buffer, containing 1% bovine serum albumin, 1 mM MgCl2, 50% glycerol, and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.
Evan G I, et al.
Molecular and Cellular Biology, 5(12), 3610-3616 (1985)
Ubiquitin ligase SYVN1/HRD1 facilitates degradation of the SERPINA1 Z variant alpha-1-antitrypsin Z variant via SQSTM1/p62-dependent selective autophagy
Feng,L, et al.
Autophagy, 13(4), 686-702 (2017)
Structural and functional insights into the lipopolysaccharide ABC transporter LptB 2 FG
Dong H, et al.
Nature Communications, 8(1), 222-222 (2017)
Novel ganglioside antigen identified by B cells in human medullary breast carcinomas: the proof of principle concerning the tumor-infiltrating B lymphocytes
Kotlan B, et al.
Journal of Immunology, 175(4), 2278-2285 (2005)
Xiaodi Tang et al.
Nature communications, 10(1), 4175-4175 (2019-09-15)
Lipopolysaccharides (LPS) of Gram-negative bacteria are critical for the defence against cytotoxic substances and must be transported from the inner membrane (IM) to the outer membrane (OM) through a bridge formed by seven membrane proteins (LptBFGCADE). The IM component LptB2FG powers the
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