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Merck
CN

A5560

Sigma-Aldrich

Anti-Water Channel Aquaporin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

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About This Item

MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

lyophilized powder

种属反应性

rat, human

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot (chemiluminescent): 1:400-1:800

UniProt登记号

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... AQP1(358)
rat ... Aqp1(25240)

一般描述

Aquaporins are transmembrane proteins composed of 6 α helices that regulate the flow of water across the membrane. AQP1 is highly expressed on the apical membrane of kidneys.
Rabbit Anti-Water Channel Aquaporin 1 antibody binds to human and rat aquaporin 1.

免疫原

synthetic peptide corresponding to amino acids 243-261 of human aquaporin 1 conjugated to KLH with glutaraldehyde. The epitope is identical in human, rodent, and cattle and only slightly different in frog.

应用

Rabbit Anti-Water Channel Aquaporin 1 antibody has been used for immunocytochemical assays. The product can also be used for immunohistochemistry and western blot.

外形

Lyophilized from phosphate buffered saline, pH 7.4, and 0.025% sodium azide

制备说明

Isolated on immobilized Protein A

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R T Boyle et al.
Bulletin of environmental contamination and toxicology, 90(3), 387-390 (2013-01-01)
We used immunocytochemical and fluorometric techniques to show that gill cells of two marine invertebrates, the crab Neohelice granulata (osmoregulator) and the clam Mesodesma mactroides (osmoconformer), increase the expression of membrane transporters [Na(+)/K(+)-ATPase and aquaporin (AQP1)] after whole-animals exposure (96 h)
Kamila Foguesatto et al.
Cell biology international, 46(6), 976-985 (2022-03-09)
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Genome biology, 7(2), 206-206 (2006-03-09)
Water is the major component of all living cells, and efficient regulation of water homeostasis is essential for many biological processes. The mechanism by which water passes through biological membranes was a matter of debate until the discovery of the
Caroline T Rocha et al.
Archives of environmental contamination and toxicology, 62(1), 56-67 (2011-04-29)
The objective of this study was to evaluate the influence of lead (Pb) on regulatory proteins linked to mechanisms of animal adaptation to polluted environments (using in vivo and in vitro tests) and to validate the in vitro assay as
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