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Merck
CN

A5508

Sigma-Aldrich

腺苷5′-磷酸硫酸盐 钠盐

≥85%

别名:

APS

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About This Item

经验公式(希尔记法):
C10H14N5O10PS
分子量:
427.28
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

生物来源

synthetic (organic)

质量水平

方案

≥85%

表单

powder

文件

see Safety & Documentation for available documents

食品过敏原

no known allergens

运输

dry ice

储存温度

−20°C

SMILES字符串

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OS(O)(=O)=O)C(O)C3O

InChI

1S/C10H14N5O10PS.Na.H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-26(18,19)25-27(20,21)22;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H,20,21,22);;

InChI key

KLZADYTZAADWRW-UHFFFAOYSA-N

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应用

腺苷 5′-磷酸硫酸钠盐已被用于酶链生物发光检测法定量测定三磷酸腺苷(ATP) 和焦磷酸盐。

生化/生理作用

腺苷5′磷酸硫酸盐 (APS) 可用作三磷酸腺苷(ATP)硫酸化酶的底物,从而在萤火虫荧光素酶ATP发光分析和其他焦磷酸盐再生依赖型检测分析中,完成指数式ATP扩增中的PP(i)-循环回路。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Norbert Kiss et al.
Lasers in medical science, 35(8), 1821-1830 (2020-05-07)
Pseudoxanthoma elasticum (PXE, OMIM 264800) is a rare autosomal recessive disorder with ectopic mineralization and fragmentation of elastin fibers. It is caused by mutations of the ABCC6 gene that leads to decreased serum levels of inorganic pyrophosphate (PPi) anti-mineralization factor.
Novel bioluminescent assay of alkaline phosphatase using adenosine-3?-phosphate-5?-phosphosulfate as substrate and the luciferin-luciferase reaction and its application
Arakawa H, et al.
Analytical biochemistry, 314(2), 206-211 (2003)
Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment
Villa BR, et al.
Circulation, 127(24), 2442-2451 (2013)
Fumika Mi-Ichi et al.
PLoS neglected tropical diseases, 13(8), e0007633-e0007633 (2019-08-20)
Amoebiasis, caused by Entamoeba histolytica infection, is a global public health problem. However, available drugs to treat amoebiasis are currently limited, and no effective vaccine exists. Therefore, development of new preventive measures against amoebiasis is urgently needed. Here, to develop
Momoko Horikoshi et al.
PLoS genetics, 11(7), e1005230-e1005230 (2015-07-02)
Reference panels from the 1000 Genomes (1000G) Project Consortium provide near complete coverage of common and low-frequency genetic variation with minor allele frequency ≥0.5% across European ancestry populations. Within the European Network for Genetic and Genomic Epidemiology (ENGAGE) Consortium, we

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