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Merck
CN

A5284

Sigma-Aldrich

8-氮鸟嘌呤

Hybri-Max, γ-irradiated, powder, BioXtra, suitable for hybridoma

别名:

8-AzaG, 2-氨基-6-氧-8-氮杂嘌呤, 2-氨基-6-羟基-8-氮杂嘌呤, 癌散

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About This Item

经验公式(希尔记法):
C4H4N6O
CAS号:
分子量:
152.11
Beilstein:
171098
EC 号:
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:

等级

Hybri-Max

无菌性

γ-irradiated

产品线

BioXtra

表单

powder

技术

cell culture | hybridoma: suitable

mp

>300 °C (lit.)

储存温度

−20°C

SMILES字符串

NC1=Nc2[nH]nnc2C(=O)N1

InChI

1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)

InChI key

LPXQRXLUHJKZIE-UHFFFAOYSA-N

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应用

用作杂交瘤细胞培养应用中的骨髓瘤选择剂。

重悬

10mL 无菌细胞培养基可复原一小瓶本品。储备液足以制备 500mL 培养基。10mg/瓶包装的最终工作浓度:130μM 8-氮鸟嘌呤。分析证书上提供了每瓶的含量。

法律信息

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

July Fong et al.
Scientific reports, 8(1), 1155-1155 (2018-01-20)
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeting
Sunirmal Paul et al.
Environmental and molecular mutagenesis, 47(5), 311-319 (2006-03-07)
Endogenous DNA damage clusters--two or more oxidized bases, abasic sites, or strand breaks within about 20 base pairs on opposing strands--can accumulate in unirradiated mammalian cells, and may be significant origins of spontaneous detrimental biological effects. Factors determining the levels
T L Bowen et al.
Journal of bacteriology, 178(9), 2521-2526 (1996-05-01)
Phosphoribosyltransferase (PRTase) and nucleoside phosphorylase (NPase) activities were detected by radiometric methods in extracts of Methanococcus voltae. Guanine PRTase activity was present at 2.7 nmol min(-1) mg of protein(-1) and had an apparent Km for guanine of 0.2 mM and
Qiao-Ling Gong et al.
Journal of molecular modeling, 18(2), 493-500 (2011-05-05)
The interaction between 8-azaguanine (8-Azan) and bovine serum albumin (BSA) in Tris-HCl buffer solutions at pH 7.4 was investigated by means of fluorescence and ultraviolet-visible (UV-Vis) spectroscopy. At 298 K and 310 K, at a wavelength of excitation (λ (ex))
Erwan Atcheson et al.
NPJ vaccines, 5, 92-92 (2020-10-22)
Malaria remains one of the world's most urgent global health problems, with almost half a million deaths and hundreds of millions of clinical cases each year. Existing interventions by themselves will not be enough to tackle infection in high-transmission areas.

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