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Merck
CN

A4378

Sigma-Aldrich

牛血清白蛋白 来源于牛血清

lyophilized powder, 1× crystallized, ≥97% (agarose gel electrophoresis)

别名:

BSA, 牛白蛋白, 牛血清白蛋白

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About This Item

CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.27

生物来源

bovine

质量水平

方案

≥97% (agarose gel electrophoresis)

表单

lyophilized powder

质量

crystallized

分子量

~66 kDa

纯化方式

cold ethanol fractionation

包装

poly bottle of

来源

USA origin

技术

ELISA: suitable

pH值(酸碱度)

7

溶解性

water: soluble (50 mg/ml)

UniProt登记号

储存温度

2-8°C

基因信息

bovine ... ALB(280717)

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一般描述

Albumin is the most abundant plasma protein in humans. High levels of albumin are associated with dehydration. Albumin turnover is seen in infants with iron deficiency anemia. Serum albumin is a reliable prognostic indicator for liver disease. Oxidative damage of albumin is associated with advanced liver disease.

应用

Bovine Serum Albumin has been:
  • as an additive in washout solution and fluorescent dye solution
  • as a supplement in Waymouth medium and modified essential medium-α (MEMα )
  • in plant extract for the protein precipitation test
  • as a component in Ringer′s solution to rinse the retinal tissue

生化/生理作用

BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。

制备说明

血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。 血清白蛋白可在采用Cohn′法的第五乙醇分级中发现。 从此,有些人便开始使用“Fraction V”这一术语来描述血清白蛋白,无论使用的是什么制备方法。 也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白,而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白,包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。 更多的纯化步骤包括结晶或木炭过滤。
通常称为 Cohn fraction V;本品采用改进的 Cohn 氏冷乙醇分级分离法制备。采用专属的结晶法进一步纯化

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Distribution of potassium conductance in mammalian Muller (glial) cells: a comparative study
Newman EA
The Journal of Neuroscience, 7(8), 2423-2432 (1987)
A revised protocol for in vitro development of mouse oocytes from primordial follicles dramatically improves their developmental competence
O'Brien MJ, et al.
Biology of Reproduction, 68(5), 1682-1686 (2003)
Effects of condensed tannins prepared from leaves of fodder plants on digestive enzymes in vitro and in the intestine of rats
Horigome T, et al.
British Journal of Urology, 60(2), 275-285 (1988)
Bingmei M Fu et al.
Microvascular research, 68(1), 51-62 (2004-06-29)
To investigate the effect of vascular endothelial growth factor (VEGF) on solute permeability of mammalian microvessels, we measured the apparent permeability (P) of various-sized solutes on the postcapillary venules of rat mesentery in vivo. Exposure to 1 nM VEGF transiently
Meghan Riddell et al.
Nature communications, 9(1), 5357-5357 (2018-12-19)
Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity protein atypical protein kinase C lambda/iota (aPKCλ) is associated with cell proliferation through unknown mechanisms. In endothelial cells, suppression of

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