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Merck
CN
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文件

A4330

Sigma-Aldrich

4'-氨甲基三氧沙林 盐酸盐

别名:

4＆＃8242;氨基甲基-4,5-＆＃8242;，8三甲基补骨脂 盐酸盐

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About This Item

经验公式（希尔记法）:
C15H15NO3 · HCl
CAS号:
62442-61-9
分子量:
293.75
MDL编号:
MFCD00134837
UNSPSC代码:
12352200
PubChem化学物质编号:
24890846
NACRES:
NA.77

形式

powder

质量水平

200

溶解性

H2O: 1 mg/mL
DMSO: 2 mg/mL

储存温度

2-8°C

SMILES字符串

CC1=CC(=O)Oc2c(C)c3oc(C)c(CN)c3cc12

InChI

1S/C15H15NO3/c1-7-4-13(17)19-14-8(2)15-11(5-10(7)14)12(6-16)9(3)18-15/h4-5H,6,16H2,1-3H3

InChI key

WBIICVGYYRRURR-UHFFFAOYSA-N

应用

4'-盐酸氨甲基三氧沙林可灭活 DNA 和 RNA 病毒，包括 HIV-1。4'-盐酸氨甲基三氧沙林在紫外光照射下可与核酸共价结合。

生化/生理作用

4'-盐酸氨甲基三氧沙林用于通过核酸交联和紫外线照射灭活 DNA 和 RNA 病毒，包括 HIV-1。

特点和优势

这种化合物是细胞凋亡研究的特色产品。 点击此处 ，发现更多特色细胞凋亡产品。访问sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子的信息。

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Carc. 2 - Skin Corr. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

分析证书(COA)

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W S Groene et al.
Journal of virological methods, 38(1), 93-102 (1992-07-01)
The use of the synthetic psoralen 4'-aminomethyl-4,5',8-trimethylpsoralen hydrochloride (AMT) is described for the inactivation of infectious rotavirus, a member of the viral family Reoviradae with a double-stranded RNA genome. This method not only provides complete inactivation of the virus but
M Beltrame et al.
The EMBO journal, 11(4), 1531-1542 (1992-04-01)
It has long been known that U3 can be isolated hydrogen bonded to pre-ribosomal RNAs, but the sites of interaction are poorly characterized. Here we show that yeast U3 can be cross-linked to 35S pre-rRNA both in deproteinized extracts and
H Du et al.
RNA (New York, N.Y.), 7(1), 133-142 (2001-02-24)
Base pairing between the 5' end of U1 snRNA and the conserved 5' splice site of pre-mRNA is important for commitment complex formation in vitro. However, the biochemical mechanisms by which pre-mRNA is initially recognized by the splicing machinery is
J A Grass et al.
Blood, 91(6), 2180-2188 (1998-04-16)
A photochemical treatment (PCT) process using a novel psoralen and long wavelength ultraviolet light (UVA, 320-400 nm) has been developed to inactivate bacteria and viruses in platelet concentrates. This study evaluated the efficacy of PCT for inactivation of leukocytes that
A A Oroskar et al.
Free radical biology & medicine, 20(5), 751-756 (1996-01-01)
The ability of scavengers of hydroxyl radical (OH radical) to modulate the photosensitized relaxation (induction of the first single-strand break) of supercoiled plasmid DNA with UVA photoactivated 4'-aminomethyl-4,5',8-trimethylpsoralen was examined by comparing the dose reduction factor (DRF: the ratio of
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