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Merck
CN

A4161

Sigma-Aldrich

牛血清白蛋白 来源于牛血清

lyophilized powder, essentially globulin free, BioReagent, suitable for cell culture

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别名:
BSA, 牛白蛋白, 牛血清白蛋白
CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.27

生物来源

bovine

质量水平

产品线

BioReagent

检测方案

≥99%

形式

lyophilized powder

分子量

~66 kDa

纯化方式

cold ethanol and heatshock fractionation

包装

poly bottle of

来源

USA origin

技术

cell culture | mammalian: suitable

杂质

essentially globulin free

pH值(酸碱度)

7

溶解性

water: soluble (50 mg/ml)

UniProt登记号

储存温度

2-8°C

基因信息

bovine ... ALB(280717)

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生化/生理作用

BSA的某些构象和初级序列表位是人类对牛肉和牛奶过敏中的可疑过敏原。

特点和优势

  • 经测试可用于细胞培养
  • 基本没有球蛋白。

制备说明

血清白蛋白可能也会被称为Fraction V。该命名惯例取自使用冷乙醇沉淀对血清蛋白进行分级的原始Cohn法。 血清白蛋白可在采用Cohn′法的第五乙醇分级中发现。 从此,有些人便开始使用“Fraction V”这一术语来描述血清白蛋白,无论使用的是什么制备方法。 也有人在使用该术语来描述通过乙醇分级方法而纯化得到血清白蛋白,而这种方法是相对于原始的Cohn法一直在得到高度的改良。Sigma-Aldrich生产和分销从各种主要方法纯化得到的血清白蛋白,包括真正的Cohn分级法、改良的乙醇分级方法、热休克和色谱法。 更多的纯化步骤包括结晶或木炭过滤。
通过热休克和乙醇分级的组合纯化

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

分析证书(COA)

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Guido Bolognesi et al.
Nature communications, 9(1), 1882-1882 (2018-05-16)
Constructing higher-order vesicle assemblies has discipline-spanning potential from responsive soft-matter materials to artificial cell networks in synthetic biology. This potential is ultimately derived from the ability to compartmentalise and order chemical species in space. To unlock such applications, spatial organisation
Mark A Petersen et al.
Neuron, 96(5), 1003-1012 (2017-11-07)
Blood-brain barrier (BBB) disruption alters the composition of the brain microenvironment by allowing blood proteins into the CNS. However, whether blood-derived molecules serve as extrinsic inhibitors of remyelination is unknown. Here we show that the coagulation factor fibrinogen activates the
Silvana Konermann et al.
Cell, 173(3), 665-676 (2018-03-20)
Class 2 CRISPR-Cas systems endow microbes with diverse mechanisms for adaptive immunity. Here, we analyzed prokaryotic genome and metagenome sequences to identify an uncharacterized family of RNA-guided, RNA-targeting CRISPR systems that we classify as type VI-D. Biochemical characterization and protein
Aseel El Hajj et al.
PloS one, 14(6), e0218812-e0218812 (2019-06-25)
The regulation of cholesterol, an essential brain lipid, ensures proper neuronal development and function, as demonstrated by links between perturbations of cholesterol metabolism and neurodegenerative diseases, including Alzheimer's disease. The central nervous system (CNS) acquires cholesterol via de novo synthesis
Melisa Herrero et al.
Neuromolecular medicine, 21(3), 303-313 (2019-05-28)
Vanishing white matter (VWM) disease (OMIM#306896) is an autosomal recessive neurodegenerative leukodystrophy caused by hypomorphic mutations in any of the five genes encoding the subunits of eukaryotic translation initiation factor 2B (eIF2B). The disease is manifested by loss of cerebral

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