product name
1-氨基苯并三唑,
检测方案
≥98% (TLC)
质量水平
形式
powder
环保替代产品得分
old score: 93
new score: 46
Find out more about DOZN™ Scoring
环保替代产品特性
Waste Prevention
Safer Solvents and Auxiliaries
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
mp
81-84 °C (lit.)
溶解性
ethanol: 49-51 mg/mL, clear, pale yellow to yellow
环保替代产品分类
SMILES字符串
Nn1nnc2ccccc12
InChI
1S/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H2
InChI key
JCXKHYLLVKZPKE-UHFFFAOYSA-N
基因信息
human ... CYP1A2(1544)
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相关类别
一般描述
我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别,在绿色化学原理、“废物预防”、“溶剂和助剂安全性”以及“事故预防化学本安性”方面取得了关键改进。点击此处查看其 DOZN 记分卡。
应用
使用1-氨基苯并三唑作为细胞色素P450酶抑制剂,研究雌性激素对H2O2诱导的老年大鼠血管平滑肌细胞早衰的影响此外,它还被用于研究17β-雌二醇雌激素受体介导的效应。
生化/生理作用
1-氨基苯并三唑(1-ABT)在药物研究中用作体外工具。它能区分P450和非P450酶系统。1-ABT通过P450酶中血红素辅基的共价改变表现出抑制作用。
细胞色素 P450 和氯过氧化物酶的自杀抑制剂。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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