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Merck
CN

A3886

Sigma-Aldrich

Aprotinin

powder

别名:

BPTI, 抑肽酶, 牛胰胰蛋白酶抑制剂, 胰蛋白酶抑制剂(碱性)

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About This Item

经验公式(希尔记法):
C284H432N84O79S7
CAS号:
分子量:
6511.44
EC 号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

product name

抑肽酶 来源于牛肺,

生物来源

bovine lung

质量水平

形式

powder

分子量

~6,500

包装

vial of 15 mg

溶解性

glycerol: 3 mg/mL, clear, colorless (equilibration buffer containing 5% glycerol)

UniProt登记号

储存温度

−20°C

InChI key

ZPNFWUPYTFPOJU-UHFFFAOYSA-N

基因信息

cow ... PTI(404172)

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应用

抑肽酶被大量用作胰蛋白酶抑制剂。
Gel filtration molecular weight marker

生化/生理作用

抑肽酶是一种竞争性丝氨酸蛋白酶抑制剂,可与酶的活性位点组成稳定的复合酶并同时对其进行封闭。 这种结合是可逆的,而且绝大多数抑肽酶-蛋白酶复合物可在极端的pH >10 or < 3水平时发生解离。 从结构上来说,抑肽酶是一种来自牛肺的单体球状蛋白,由58个氨基酸组成并排列在具有三个交联二硫键的单个多肽链中。

单位定义

一个胰蛋白酶抑制剂单位(TIU)可将两个胰蛋白酶单位的活性降低50%,而其中一个胰蛋白酶单位在pH 7.8和25℃下可每分钟水解1.0 μ摩尔的N-α-苯甲酰基-DL-精氨酸对硝基苯胺。另一种常用的单位是KIU,而1 TIU = 1,300 KIU。

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

动植物源性产品

分析证书(COA)

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