A3484
Anti-ATG4A antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-APG4 autophagy 4 homolog A, Anti-APG4A, Anti-AUT-like 2, Anti-AUTL2, Anti-Autophagin 2, Anti-Autophagy related 4 homolog A, Anti-Autophagy-related cysteine endopeptidase 2, Anti-Cysteine endopeptidase, ATG4
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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP
Citations:
1
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~45 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
immunoprecipitation (IP): 5-10 μg using lysate of HEK-293T cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ATG4A(115201)
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General description
Autophagy related 4A, cysteine peptidase (ATG4A or APG4A) is a C-54 cysteine protease that also belongs to the family of autophagin proteins. ATG4A is involved in cellular autophagy and has been studied as a target for cancer therapy. Rabbit anti-ATG4A antibody binds to human ATG4A.
Immunogen
synthetic peptide corresponding to amino acids 100-114 of human ATG4A, conjugated to KLH. The corresponding sequence differs by 2 amino acids in mouse and rat.
Application
Rabbit anti-ATG4A antibody can be used for immunoprecipitation assays at 5-10μg using HEK-293T cell lysates.
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Vidya Niranjan et al.
International journal of computational biology and drug design, 3(4), 271-286 (2011-02-08)
Autophagy is a biological process involved in the intracellular destruction of endogenous proteins and has been suggested to be essential for cell homeostasis as well as for cell remodelling. Autophagy selectively eradicates damaged cytoplasmic components like injured mitochondria, which increases
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