A3401
Ala-Ala-Phe-7-氨基-4-甲基香豆素
protease substrate
别名:
H-Ala-Ala-Phe-AMC
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C25H28N4O5
化学文摘社编号:
分子量:
464.51
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
产品名称
Ala-Ala-Phe-7-氨基-4-甲基香豆素, protease substrate
InChI
1S/C25H28N4O5/c1-14-11-22(30)34-21-13-18(9-10-19(14)21)28-25(33)20(12-17-7-5-4-6-8-17)29-24(32)16(3)27-23(31)15(2)26/h4-11,13,15-16,20H,12,26H2,1-3H3,(H,27,31)(H,28,33)(H,29,32)
SMILES string
CC(N)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
InChI key
FVRLYIFIDKXFHU-UHFFFAOYSA-N
assay
≥98% (TLC)
form
powder
solubility
ethanol: 20 mg/mL, clear, colorless to light yellow
storage temp.
2-8°C
Quality Level
Application
丙氨酸-丙氨酸-苯丙氨酸-7-酰胺基-4-甲基香豆素已被用于：
- 酶促反应混合液的制备
- 启动三肽基肽酶-1 (TPP1) 酶活性测定中的酶反应
- 启动溶酶体水解酶活性测定中的测定反应
General description
丙氨酸-丙氨酸-苯丙氨酸-7-酰胺基-4-甲基香豆素是蛋白水解活性的荧光底物。是带正电荷的底物分子。
糜蛋白酶和三肽基肽酶 ii 的底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Raffaella Di Giacopo et al.
Journal of the neurological sciences, 356(1-2), 65-71 (2015-07-06)
This work investigated the molecular cause responsible for a late-onset parkinsonism-dystonia phenotype in three Italian siblings, and clinically characterize this condition. Extensive neurophysiological and neuroradiological exams were performed on the three sibs. Most frequent late-onset metabolic diseases were ruled out
R M Bålöw et al.
The Journal of biological chemistry, 261(5), 2409-2417 (1986-02-15)
An extralysosomal tripeptide-releasing aminopeptidase was recently discovered in rat liver (Bålöw, R.-M., Ragnarsson, U., and Zetterqvist, O. (1983) J. Biol. Chem. 258, 11622-11628). In the present work this tripeptidyl peptidase is shown to occur in several rat tissues and in
Effect of interfacial properties on the activation volume of adsorbed enzymes
Schuabb V, et al.
Colloids and Surfaces. B, Biointerfaces, 140, 497-504 (2016)
Accumulation of polyubiquitylated proteins in response to Ala-Ala-Phe-chloromethylketone is independent of the inhibition of tripeptidyl peptidase II
Villasevil E M, et al.
Biochimica et Biophysica Acta - Molecular Cell Research, 1803(9), 1094-1105 (2010)
NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson?s disease
Pal R, et al.
Scientific reports, 6, 22866-22866 (2016)
商品
Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持