所有图片(2)
About This Item
经验公式（希尔记法）:
C15H20O3
CAS号:
分子量:
248.32
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.25
推荐产品
生物来源
Atractylodes macrocephala Koidz.
质量水平
方案
≥98% (HPLC)
表单
powder or crystals
颜色
white to off-white
溶解性
methanol: 1 mg/mL, clear, colorless
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
2-8°C
SMILES字符串
CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C[C@]2(O)OC1=O
InChI
1S/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1
InChI key
FBMORZZOJSDNRQ-GLQYFDAESA-N
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一般描述
Atractylenolide III is a biologically active sesquiterpene compound, extracted from the roots of Atractylodes macrocephala Koidzumi.
应用
Atractylenolide III has been used to examine its effects on the energy metabolism in the skeletal muscles of mouse.
Atractylenolide III, a sesquiterpenoid, is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide III may be used and studied as an inhibitor of aromatases and inducer of apoptosis. Atractylenolide III may be used to study its sonic hedgehog pathway dependent mechanism of action as an inducer of chondrogenic differentiation. Atractylenolide III may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma.
生化/生理作用
Atractylenolide III has been shown to possess anti-inflammatory effects and also offers gastroprotection. It also shows acaricidal properties and hence has the potential to be used as an agent for the control of dust mites. Atractylenolide III is capable of regulating the secretion and expression of Interleukin-6, thereby mediating the immune response caused by mast cells.
Atractylenolide III possesses anti-inflammatory and anticancer properties.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Xu Wang et al.
Journal of ethnopharmacology, 250, 112397-112397 (2019-12-13)
Ling-Gui-Zhu-Gan Decoction (LGZGD) formula, derived from traditional Chinese medicine (TCM), has definitive clinical efficacy in the treatment of heart failure (HF) in China. However, little is known of the underlying mechanism of LGZGD. The aim of this work was to
Seung-Hyun Jeong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1126-1127, 121743-121743 (2019-08-12)
The purpose of this study was to develop a method for simultaneous analysis of fourteen major active components in Gumiganghwal-tang tablet widely prescribed for cold related diseases using UPLC-ESI-MS/MS. Twelve of these 14 components were separated using 0.1% formic acid
Yuanyuan Fu et al.
Journal of pharmaceutical and biomedical analysis, 174, 595-607 (2019-07-02)
Banxia-Baizhu-Tianma decoction (BBTD) is a compound formulae of traditional Chinese medicine (TCM), which has been clinically used for treatments of neural vertigo, hypertension and epilepsy with a long history. In this study, with an ultra-fast liquid chromatography coupled with quadrupole
Xican Li et al.
Biological & pharmaceutical bulletin, 35(8), 1328-1335 (2012-08-07)
Molecules that enhance chondrogenic differentiation in mesenchymal stem cells (MSCs) were identified and isolated using an in vitro Gli reporter gene assay in MSCs incorporating a Sonic Hedgehog (Shh) target. Atractylenolide III, which promoted Gli1-mediated transcriptional activity, was isolated from
Yue Qiu et al.
Evidence-based complementary and alternative medicine : eCAM, 2019, 1392020-1392020 (2020-01-18)
Gastroesophageal reflux disease (GERDs) is a common chronic digestive system disease, in which the symptoms of reflux esophagitis (RE) seriously affect the quality of life. We aimed to study the therapeutic effect of Zhujie Hewei granules (ZHG) on reflux esophagitis
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