推荐产品
质量水平
检测方案
≥98%
形式
powder
溶解性
H2O: 1 mg/mL, clear, colorless
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
2-8°C
SMILES字符串
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(O)C=C3)[C@H]1O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4
InChI
1S/C21H22O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-26,28-29H,1H3/t7-,15-,17+,18+,19-,20+,21-/m0/s1
InChI key
ZROGCCBNZBKLEL-MFSALPCASA-N
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一般描述
Astilbin belongs to the class of dihydroflavanol compounds and is the chief biologically active component of Rhizoma Smilacis Glabrae (RSG) extract. RSG is obtained from the dried rhizome of Smilax Glabra Roxb.
应用
Astilbin from Engelhardtia roxburghiana, a flavonoid phytochemical with antibacterial activity, may be used to study its pharmacology and the effects of its antiproliferative activities versus a variety of cell types.
生化/生理作用
Astilbin exerts various biological activities such as anti-oxidative, anti-bacterial, and inhibition of contact hypersensitivity. Also, it shows insecticidal, anti-oedematogenic, antinociceptive and antidepressant properties. It has an inhibitory effect on the aldose reductase enzyme, the accumulation of sorbitol, and a protective effect on the liver. Astilbin is helpful against autoimmune diseases such as rheumatoid arthritis due to its ability to reduce matrix metalloproteinase (MMP) activity and Nitric oxide production in T lymphocytes.
Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Luciane G Batista Pereira et al.
Pest management science, 58(5), 503-507 (2002-05-10)
Astilbin was isolated in high yield from Dimorphandra mollis, and its insecticidal and growth inhibiting activity by stomach ingestion were evaluated against Anticarsia gemmatalis and Spodoptera frugiperda. The insecticidal activity of astilbin, the weight reduction of the larval phase and
Xiao-Ya Shang et al.
Journal of Asian natural products research, 14(10), 966-972 (2012-10-11)
A new dihydroflavonol glycoside dimer 6,6-bisastilbin (1) and a new nitrile-containing metabolite (Z)-5α,6β-dihydroxy-4β-methoxy-2-cyclohexene-Δ(1,α)-acetonitrile (2), together with three known analogs, bauhinin, bauhinilide, and dehydrodicatechin A, have been isolated from an ethanol extract of Bauhinia aurea. Their structures were determined by spectroscopic
Nicolas Landrault et al.
Journal of agricultural and food chemistry, 50(7), 2046-2052 (2002-03-21)
Phenolics from grapes and wines can play a role against oxidation and development of atherosclerosis. Stilbenes have been shown to have cancer chemopreventive activity and to protect lipoproteins from oxidative damage. A method for the direct determination of stilbene oligomers
Lvyi Chen et al.
Planta medica, 77(16), 1769-1773 (2011-05-27)
Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L. The effects and possible mechanisms of astilbin on hyperuricemia and nephropathy rats were elucidated in this study. Different dosages of astilbin (1.25, 2.5, and 5.0 mg/kg) were
Guang Yang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1049-1050, 41-50 (2017-03-08)
An analytical approach including fingerprint, quantitative analysis and rapid screening of anti-oxidative components was established and successfully applied for the comprehensive quality control of Rhizoma Smilacis Glabrae (RSG), a well-known Traditional Chinese Medicine with the homology of medicine and food.
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