A2862
Astilbin from Engelhardtia roxburghiana
≥98%
别名:
Astilbin, Dihydroquercetin 3-rhamnoside, Taxifolin 3-rhamnoside
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C21H22O11
化学文摘社编号:
分子量:
450.39
UNSPSC Code:
12352200
NACRES:
NA.25
MDL number:
InChI
1S/C21H22O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-26,28-29H,1H3/t7-,15-,17+,18+,19-,20+,21-/m0/s1
SMILES string
O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(O)C=C3)[C@H]1O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4
InChI key
ZROGCCBNZBKLEL-MFSALPCASA-N
assay
≥98%
form
powder
solubility
H2O: 1 mg/mL, clear, colorless
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
Quality Level
General description
Astilbin belongs to the class of dihydroflavanol compounds and is the chief biologically active component of Rhizoma Smilacis Glabrae (RSG) extract. RSG is obtained from the dried rhizome of Smilax Glabra Roxb.
Application
Astilbin from Engelhardtia roxburghiana, a flavonoid phytochemical with antibacterial activity, may be used to study its pharmacology and the effects of its antiproliferative activities versus a variety of cell types.
Biochem/physiol Actions
Astilbin exerts various biological activities such as anti-oxidative, anti-bacterial, and inhibition of contact hypersensitivity. Also, it shows insecticidal, anti-oedematogenic, antinociceptive and antidepressant properties. It has an inhibitory effect on the aldose reductase enzyme, the accumulation of sorbitol, and a protective effect on the liver. Astilbin is helpful against autoimmune diseases such as rheumatoid arthritis due to its ability to reduce matrix metalloproteinase (MMP) activity and Nitric oxide production in T lymphocytes.
Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Guoyan Liang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 59, 152772-152772 (2019-04-22)
Rhizoma smilacis glabrae (RSG, tufuling) has been widely used in traditional Chinese medicine for deoxidation, dampness relief, and easing joint movement. The chemical composition of RSG has been systematically confirmed, and some of its compounds have been revealed to possess
Yinjie Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(12), 1859-1861 (2012-09-25)
To establish a SPE-HPLC method for analyzing astilbin in rats serum and explore the effects of Yinxieling (YXL) prescription and Smilacis Glabrae Rhizoma on the pharmacokinetic characteristics of effective components. Male Sprague-dawley rats were administrated YXL and Smilacis Glabrae Rhizoma
Antioxidant activity of Rhizoma Smilacis Glabrae extracts and its key constituent-astilbin
Zhang QF, et al.,
Food Chemistry, 115(1), 297-303 (2009)
Mingjian Fei et al.
The Journal of allergy and clinical immunology, 116(6), 1350-1356 (2005-12-13)
IL-10 is known as a negative regulator for inflammatory diseases, including contact dermatitis. However, only a few drug candidates are reported to induce endogenous IL-10. We sought to elucidate a new mechanism underlying the immunosuppressive properties of astilbin through negative
O Mezghrani et al.
Die Pharmazie, 66(10), 754-760 (2011-10-27)
The main purpose of this research work was to design an optimized self micro-emulsifying drug delivery system (SMEDDS) to enhance the bioavailability of the poor water soluble drug, astilbin. The solubility of astilbin was evaluated in various vehicles. Pseudoternary phase
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持