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质量水平
方案
≥98% (HPLC)
表单
powder
技术
HPLC: suitable
颜色
white
mp
160 °C
溶解性
water: 50 mg/mL, clear, colorless
储存温度
2-8°C
SMILES字符串
CC(=O)N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O
InChI
1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8?/m1/s1
InChI key
OVRNDRQMDRJTHS-KEWYIRBNSA-N
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相关类别
一般描述
N-乙酰-D-半乳糖胺 (GalNAc) 是一种氨基糖，是许多 O-连接和N-连接聚糖结构的组成部分。作为尿苷二磷酸 (UDP)-GalNAc，GalNAc是许多丝氨酸和苏氨酸残基蛋白质糖基化的初始O连接糖。
应用
N-乙酰-D-半乳糖胺已用于：
- 用作双花扁豆凝集素 (DBA) 半抗原糖，用于凝集素珠结合测定
- 通过凝集素印迹抑制评估凝集素结合的特异性
- 免疫组织化学预吸附紫藤凝集素
N-乙酰-D-半乳糖胺（GalNAc）是一种氨基糖，是许多O-连接和N连接聚糖结构的组分。 作为UDP-GalNAc，GalNAc是许多蛋白质糖基化丝氨酸和苏氨酸残基的起始O-连接糖。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Malte Lenders et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 32(12), 2090-2097 (2016-09-30)
Renal and cardiac involvement is responsible for substantial morbidity and mortality in Fabry disease (FD). We analysed the incidence of FD-related renal, cardiac and neurologic end points in patients with FD on long-term enzyme replacement therapy (ERT). A retrospective analysis
Yuki Kuramoto et al.
Journal of molecular and cellular cardiology, 121, 256-265 (2018-07-27)
Fabry disease is an X-linked disease caused by mutations in α-galactosidase A (GLA); these mutations result in the accumulation of its substrates, mainly globotriaosylceramide (Gb3). The accumulation of glycosphingolipids induces pathogenic changes in various organs, including the heart, and Fabry
P Van den Steen et al.
Critical reviews in biochemistry and molecular biology, 33(3), 151-208 (1998-07-23)
The biosynthesis, structures, and functions of O-glycosylation, as a complex posttranslational event, is reviewed and compared for the various types of O-glycans. Mucin-type O-glycosylation is initiated by tissue-specific addition of a GalNAc-residue to a serine or a threonine of the
F H M van Zelst et al.
Faraday discussions, 218(0), 219-232 (2019-05-24)
To detect and characterise compounds in complex matrices, it is often necessary to separate the compound of interest from the matrix before analysis. In our previous work, we have developed the coupling of supercritical fluid chromatography (SFC) with nuclear magnetic
Kai J Rogers et al.
PLoS neglected tropical diseases, 13(12), e0007819-e0007819 (2019-12-12)
Ebolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical trials. A critical step towards development of effective therapeutics is a better understanding of factors
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