biological source
synthetic
Quality Level
form
powder
concentration
691-806 μg/mg (dry)
color
white to off-white
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycobacteria
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
OS(O)(=O)=O.NCC[C@@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
InChI
1S/C22H43N5O13.H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);(H2,1,2,3,4)/t6-,7+,8+,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;/m0./s1
InChI key
HIBICIOPDUTNRR-BOEHXBESSA-N
General description
化学结构:氨基糖苷类
Application
阿米卡星是一种氨基糖苷类抗生素,常用于治疗耐药性分枝杆菌 。 它被用于研究抗生素的生物体定向以及耐药性 。
Biochem/physiol Actions
抗菌谱: 革兰氏阴性和革兰氏阳性菌。
阿米卡星通过与30S核糖体亚基结合并诱导mRNA误读来防止细菌蛋白质合成。
Analysis Note
阿米卡星:硫酸盐比例为1:1.8
Other Notes
保存于密闭容器内,置于干燥通风处。
氨基糖苷类抗生素。 卡那霉素的衍生物。
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Justin R Lenhard et al.
Diagnostic microbiology and infectious disease, 98(1), 115080-115080 (2020-07-04)
The objective of this study was to utilize a co-culture hollow-fiber infection model (HFIM) to characterize the interplay between a small, difficult-to-detect, New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae (NDM-Kp) minor population and a larger K. pneumoniae carbapenemase (KPC)-producing K. pneumoniae population
A M Lovering et al.
The Journal of antimicrobial chemotherapy, 43(5), 719-721 (1999-06-26)
Antibiotic-free human serum was spiked with known concentrations of liposomal amikacin and assayed on the Abbott TDx System, using polarization fluoroimmuno assay (PFIA) kits from Abbott Laboratories, Oxis and Sigma. Although all three kits gave a linear response, the Abbott
Targeted Delivery of Amikacin into Granuloma.
Ana Montes-Worboys, et al.
American Journal of Respiratory Cell and Molecular Biology, 182, 1546-1553 (2010)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A2324-5G | 04061835517978 |
