DMT-2′O-Methyl-rA(bz) 磷酰胺

生物来源

non-animal source (no BSE/TSE risk)

质量水平

300

产品线

Proligo Reagents

检测方案

≥99% (³¹P-NMR)
≥99.0% (reversed phase HPLC)

形式

powder

技术

oligo synthesis: suitable

杂质

≤0.1% single unspecified Impurity (reversed phase HPLC)
≤0.3% mA2 (reversed phase HPLC, Hydrolysate)
≤0.3% mA3 (reversed phase HPLC, DMT-rA(bz)me)
≤0.3% water content (Karl Fischer)
≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR)
≤1.0% mA1 (reversed phase HPLC, DMT-rA(bz)me-DMT)
≤3% residual Solvent content

颜色

white to off-white

λ

conforms (UV/VIS Identity)

适用性

conforms to structure for H-NMR
conforms to structure for LC-MS

相容性

configured for ABI

核苷分析

base: adenosine
base protecting group: benzoyl
2' protecting group: methyl
5' protecting group: DMT
deprotection: standard

储存温度

2-8°C

SMILES字符串

CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1n5cnc6c(NC(=O)c7ccccc7)ncnc56

InChI

1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-42-40(62-47(43(42)59-7)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1

InChI key

AZCGOTUYEPXHMJ-PSVHYZMASA-N