DMT-2′O-TBDMS-rA (bz) 亚磷酰胺

生物来源

non-animal source (no BSE/TSE risk)

质量水平

300

产品线

Proligo Reagents

方案

≥99% (³¹P-NMR)
≥99.0% (reversed phase HPLC)

表单

powder

技术

oligo synthesis: suitable

杂质

≤0.3 wt. % water content (Karl Fischer)
≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR)
≤0.5% single Impurity (reversed phase HPLC)
≤3 wt. % residual Solvent content

颜色

white to off-white

λ

conforms (UV/VIS Identity)

适用性

conforms to structure for H-NMR
conforms to structure for LC-MS

核苷分析

base: adenosine
base protecting group: benzoyl
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard

储存温度

−20°C

SMILES字符串

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7

InChI

1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1

InChI key

FFXHNCNNHASXCT-RFMFGJHUSA-N