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Merck
CN

A2027

Sigma-Aldrich

L-精氨酸-7-酰胺-4-甲基香豆素 盐酸盐

cathepsin H substrate

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别名:
Arginine 4-methyl-7-coumarylamide
经验公式(希尔记法):
C16H21N5O3
CAS号:
分子量:
331.37
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.83

质量水平

检测方案

≥97% (TLC)

形式

powder

溶解性

acetic acid: water (1:1): 50 mg/mL, clear, colorless to light yellow

储存温度

−20°C

SMILES字符串

Cl.CC1=CC(=O)Oc2cc(NC(=O)[C@@H](N)CCCNC(N)=N)ccc12

InChI

1S/C16H21N5O3.ClH/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19;/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20);1H/t12-;/m0./s1

InChI key

PFLMUQNBZRXRHD-YDALLXLXSA-N

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应用

L-精氨酸-7-酰胺-4-甲基香豆素盐酸盐已被用作来自大鼠肌肉匀浆和肌浆提取物的组织蛋白酶 H 的底物。它还被用作来自水蚤匀浆的精氨酸氨基肽酶和来自弓形虫的重组氨基肽酶的底物。

生化/生理作用

L-精氨酸-7-酰胺-4-甲基香豆素盐酸盐是蛋白酶底物。它是组织蛋白酶 H 的特异性底物,而不是组织蛋白酶 L 和 B 的特异性底物。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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