推荐产品
生物来源
synthetic (Organic)
质量水平
方案
≥90%
表单
powder
溶解性
H2O: soluble~-50 g/L
储存温度
−20°C
SMILES字符串
[Na+].[Na+].[Na+].CC(=O)CC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP([O-])(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP([O-])([O-])=O)n2cnc3c(N)ncnc23
InChI
1S/C25H40N7O18P3S/c1-13(33)8-16(35)54-7-6-27-15(34)4-5-28-23(38)20(37)25(2,3)10-47-53(44,45)50-52(42,43)46-9-14-19(49-51(39,40)41)18(36)24(48-14)32-12-31-17-21(26)29-11-30-22(17)32/h11-12,14,18-20,24,36-37H,4-10H2,1-3H3,(H,27,34)(H,28,38)(H,42,43)(H,44,45)(H2,26,29,30)(H2,39,40,41)/t14-,18-,19-,20+,24-/m1/s1
InChI key
OJFDKHTZOUZBOS-CITAKDKDSA-N
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应用
乙酰乙酰-CoA硫解酶EC 2.3.1.9的底物；在无活菌素的生物合成中发挥作用。
乙酰乙酰辅酶A（乙酰乙酰-CoA）可用作许多酶的底物，包括：在反向缩合反应中产生乙酰辅酶A的乙酰乙酰-CoA硫解酶（EC2.3.1），以及在甲羟戊酸途径中产生3-羟基-3-甲基戊二酰（HMG）辅酶A并导致萜类化合物生物合成的（3-羟基-3-甲基戊二酰辅酶A（CoA）合成酶（HMGCS））。 乙酰乙酰-CoA也是微生物中聚-β-羟基丁酸酯聚合物的前体。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Rongcan Luo et al.
Signal transduction and targeted therapy, 6(1), 325-325 (2021-09-02)
Alzheimer's disease (AD) is characterized by progressive synaptic dysfunction, neuronal death, and brain atrophy, with amyloid-β (Aβ) plaque deposits and hyperphosphorylated tau neurofibrillary tangle accumulation in the brain tissue, which all lead to loss of cognitive function. Pathogenic mutations in
Tamay Seker et al.
Applied microbiology and biotechnology, 67(1), 119-124 (2004-09-28)
The mevalonate pathway plays an important role in providing the cell with a number of essential precursors for the synthesis of biomass constituents. With respect to their chemical structure, the metabolites of this pathway can be divided into two groups:
Petri Kursula et al.
Biochemistry, 41(52), 15543-15556 (2002-12-27)
Biosynthetic thiolase catalyzes the formation of acetoacetyl-CoA from two molecules of acetyl-CoA. This is a key step in the synthesis of many biological compounds, including steroid hormones and ketone bodies. The thiolase reaction involves two chemically distinct steps; during acyl
Ethan I Lan et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(16), 6018-6023 (2012-04-05)
While conservation of ATP is often a desirable trait for microbial production of chemicals, we demonstrate that additional consumption of ATP may be beneficial to drive product formation in a nonnatural pathway. Although production of 1-butanol by the fermentative coenzyme
Ken'ichiro Matsumoto et al.
Bioscience, biotechnology, and biochemistry, 75(2), 364-366 (2011-02-11)
A biosynthetic pathway for poly(3-hydroxybutyrate) [P(3HB)] was developed in Escherichia coli and Corynebacterium glutamicum by an acetoacetyl-coenzyme A (CoA) synthase (AACS) recently isolated from terpenoid-producing Streptomyces sp. strain CL190. Expression of AACS led to significant productions of P(3HB) in E.
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