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Merck
CN

A1556

Sigma-Aldrich

15-O-乙酰基-4-脱氧瓜萎镰菌醇 来源于禾谷镰刀菌

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别名:
15-乙酰氧基-3α,7α-二羟基-12,13-环氧单端孢霉-9-烯-8-酮
经验公式(希尔记法):
C17H22O7
CAS号:
分子量:
338.35
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.77

形式

powder

质量水平

储存温度

2-8°C

SMILES字符串

CC(=O)OC[C@]12[C@H](O)C(=O)C(C)=C[C@H]1O[C@@H]3[C@H](O)C[C@@]2(C)[C@]34CO4

InChI

1S/C17H22O7/c1-8-4-11-16(6-22-9(2)18,13(21)12(8)20)15(3)5-10(19)14(24-11)17(15)7-23-17/h4,10-11,13-14,19,21H,5-7H2,1-3H3/t10-,11-,13-,14-,15-,16-,17+/m1/s1

InChI key

IDGRYIRJIFKTAN-HTJQZXIKSA-N

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一般描述

15-O-乙酰基-4-脱氧雪腐镰刀菌烯醇(15-ADON)属于 B 型古猿真菌毒素。它在生长在燕麦、小麦、黑麦、玉米和大麦等谷物上的镰刀菌属真菌中大量存在。
15-O-乙酰基-4-脱氧雪腐镰刀菌烯醇(15-ADON)是一种 B 型古猿真菌毒素。它在生长在燕麦、小麦、黑麦、玉米和大麦等谷物上的镰刀菌属真菌中大量存在。

应用

15-O-乙酰基-4-脱氧雪腐镰刀菌烯醇(15-ADON)已用作三烯化合物,用在双单倍体亚群研究中处理小麦卵巢。

生化/生理作用

人类和牲畜食用15-O-乙酰基-4-脱氧雪腐镰刀菌烯醇(15-ADON)可能有害。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

高风险级别生物产品--毒素类产品

分析证书(COA)

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Helle Katrine Knutsen et al.
EFSA journal. European Food Safety Authority, 15(9), e04718-e04718 (2017-09-11)
Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring predominantly in cereal grains. Following the request of the European Commission, the CONTAM Panel assessed the risk to animal and human health related to DON, 3-acetyl-DON (3-Ac-DON), 15-acetyl-DON (15-Ac-DON) and
Trichothecene-mediated in vitro selection in wheat for reduced mycotoxin accumulation caused by Fusarium graminearum
Eudes F, et al.
Canadian Journal of Plant Science , 88(6), 1115-1125 (2008)
Pianpian Yan et al.
Toxins, 12(3) (2020-04-03)
Deoxynivalenol (DON), along with 3-acetyl-deoxynivalenol (3-ADON) and 15-acetyl-deoxynivalenol (15-ADON), occur in grains and cereal products and is often hazardous to humans and livestock. In this study, 579 wheat samples and 606 maize samples intended for consumption were collected from China
J Merhej et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 27(5), 710-717 (2010-02-20)
Reducing production of type B trichothecenes by Fusarium graminearum on cereals is necessary to control contamination, prevent yield reduction and protect human and animal health. Thus, an understanding of how trichothecene biosynthesis is induced is essential. The effect of ambient
María Marta Reynoso et al.
International journal of food microbiology, 145(2-3), 444-448 (2011-02-16)
Argentina is the fourth largest exporter of wheat in the world. The main pathogen associated with Fusarium Head Blight (FHB) of wheat in Argentina is Fusarium graminearum lineage 7 also termed F. graminearum sensu stricto in the F. graminearum species

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