一般描述
山羊多克隆抗白蛋白抗血清通过针对正常人血清和人白蛋白的免疫电泳对人白蛋白具有免疫特异性。特异性抗体的识别性和纯度可通过免疫电泳(IEP)进行确定。 抗血清的电泳,然后针对抗山羊血清的扩散会导致多个沉淀弧,而针对抗山羊IgG,则会导致γ-区域的单个沉淀ARC。
白蛋白是肝细胞产生的主要蛋白质,占人血清总蛋白质含量的一半以上。 许多其他体液也含有白蛋白。 已经提出了血清白蛋白的三个主要功能: 维持渗透性压力,运输各种物质和氨基酸的内源性来源。 白蛋白降解的主要部位尚不清楚,但蛋白几乎可以被体内的每个器官代谢。 血清白蛋白水平的测定是临床医学中广泛使用的筛选测试。 血清白蛋白水平降低可能提示疾病状态,例如营养不良、肝硬化、肾病综合征、糖尿病、胃肠道和肝脏疾病、各种热灼伤和肺部疾病。
免疫原
纯化的人白蛋白
应用
山羊抗血清白蛋白多克隆抗体可用于标记白蛋白,通过免疫细胞化学和免疫组化(IHC)技术进行检测和定量测定。它被用作探针来确定各种临床适应症中白蛋白的存在和作用。
外形
由 0.01M 的磷酸缓冲盐溶液 (pH 7.2) 冻干
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Journal of chromatography. A, 1416, 112-120 (2015-09-19)
A method combining on-line immunoextraction microcolumns with high-performance affinity chromatography (HPAC) was developed and tested for use in examining drug-protein interactions with normal or modified proteins. Normal human serum albumin (HSA) and glycated HSA were used as model proteins for
Journal of chromatography. A, 1638, 461683-461683 (2020-11-24)
Diabetes is characterized by elevated levels of blood glucose, which can result in the modification of serum proteins. The modification of a protein by glucose, or glycation, can also lead to the formation of advanced glycated end-products (AGEs). One protein
Current protocols, 3(8), e867-e867 (2023-08-23)
Immunoaffinity chromatography (IAC) is a type of liquid chromatography that uses immobilized antibodies or related binding agents as selective stationary phases for sample separation or analysis. The strong binding and high selectivity of antibodies have made IAC a popular tool
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121812-121812 (2019-12-17)
An on-line purification and entrapment system was developed that could extract a protein from a sample such as serum and entrap this protein within a small column for use in high-performance affinity chromatography. Human serum albumin (HSA) was employed as
Journal of applied physiology (Bethesda, Md. : 1985), 82(6), 2003-2010 (1997-06-01)
Near-term newborn rabbits were exposed via the airways to a monoclonal antibody to surfactant protein B and ventilated for 0-120 min. Control animals received nonspecific rabbit or mouse immunoglobulin G, saline, or no material via the airways. Administration of the
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