A0752
腺苷 5′-二磷酸核糖 钠盐
≥93%, from yeast (candida utilis), powder
别名:
ADPR, 腺苷二磷酸核糖
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关于此项目
经验公式（希尔记法）:
C15H23N5O14P2
化学文摘社编号:
分子量:
559.32
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
产品名称
腺苷 5′-二磷酸核糖 钠盐, ≥93%
assay
≥93%
form
powder
biological source
yeast (candida utilis)
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC(O)C(O)C(O)C=O)C(O)C3O
InChI
1S/C15H23N5O14P2.Na.H/c16-13-9-14(18-4-17-13)20(5-19-9)15-12(26)11(25)8(33-15)3-32-36(29,30)34-35(27,28)31-2-7(23)10(24)6(22)1-21;;/h1,4-8,10-12,15,22-26H,2-3H2,(H,27,28)(H,29,30)(H2,16,17,18);;
InChI key
NWPVXDZLQTURKI-UHFFFAOYSA-N
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
Quality Level
Application
使用5′-脱氧-5′-(甲硫基)腺苷：
- 给出一系列烟酰胺腺嘌呤二核苷酸(NADH)
- 氧化速率，用于呼吸链复合体(CI/CIII/CIV)
- CI/替代(AOX) 通路
- 测定聚腺苷二磷酸核糖甘油水解酶活性
- 聚腺苷二磷酸核糖(PAR)结合竞争性分析
- 氧化酶(AOX)通路
- 测定聚腺苷二磷酸核糖甘油水解酶活性
- 聚腺苷二磷酸核糖(PAR)结合竞争性分析
Biochem/physiol Actions
通过聚腺苷二磷酸核糖聚合酶(PARP)家族成员形成聚腺苷二磷酸核糖(ADP-ribose)时，腺苷5′-二磷酸核糖(ADP-Ribose)用作底物的基础嵌段。聚腺苷酸核糖的形成和降解是脱氧核糖核酸修复和凋亡信号的重要组成部分。ADP-核糖启动瞬时受体电位亚家族褪黑素 2 型 (TRPM2)，即 Na+、Ca2+和K+阳离子通道。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
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商品
LC-MS/MS method quantifies similar polar nucleotide activated sugars using Supel™ Carbon LC column for simultaneous analysis.
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