推荐产品
生物来源
yeast (candida utilis)
质量水平
检测方案
≥93%
形式
powder
储存温度
−20°C
SMILES字符串
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC(O)C(O)C(O)C=O)C(O)C3O
InChI
1S/C15H23N5O14P2.Na.H/c16-13-9-14(18-4-17-13)20(5-19-9)15-12(26)11(25)8(33-15)3-32-36(29,30)34-35(27,28)31-2-7(23)10(24)6(22)1-21;;/h1,4-8,10-12,15,22-26H,2-3H2,(H,27,28)(H,29,30)(H2,16,17,18);;
InChI key
NWPVXDZLQTURKI-UHFFFAOYSA-N
应用
使用5′-脱氧-5′-(甲硫基)腺苷:
- 给出一系列烟酰胺腺嘌呤二核苷酸(NADH)
- 氧化速率,用于呼吸链复合体(CI/CIII/CIV)
- CI/替代(AOX) 通路
- 测定聚腺苷二磷酸核糖甘油水解酶活性
- 聚腺苷二磷酸核糖(PAR)结合竞争性分析
- 氧化酶(AOX)通路
- 测定聚腺苷二磷酸核糖甘油水解酶活性
- 聚腺苷二磷酸核糖(PAR)结合竞争性分析
生化/生理作用
通过聚腺苷二磷酸核糖聚合酶(PARP)家族成员形成聚腺苷二磷酸核糖(ADP-ribose)时,腺苷5′-二磷酸核糖(ADP-Ribose)用作底物的基础嵌段。聚腺苷酸核糖的形成和降解是脱氧核糖核酸修复和凋亡信号的重要组成部分。ADP-核糖启动瞬时受体电位亚家族褪黑素 2 型 (TRPM2),即 Na+、Ca2+和K+阳离子通道。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
Journal of lipid research, 60(7), 1225-1235 (2019-04-17)
Radiation treatment failure or relapse after initial response to chemotherapy presents significant clinical challenges in cancer patients. Escape from initial courses of treatment can involve reactivation of embryonic developmental stages, with the formation of polynuclear giant cancer cells (PGCCs). This
Structure?Activity Relationship of Adenosine 5?-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists
Journal of Medicinal Chemistry, 56(24) (2013)
Monitoring poly (ADP-ribosyl) glycohydrolase activity with a continuous fluorescent substrate
Cell Chemical Biology, 25(12), 1562-1570 (2018)
Mitochondrial supercomplexes do not enhance catalysis by quinone channeling
Cell Metabolism, 28(3), 525-531 (2018)
Journal of cellular biochemistry, 117(5), 1136-1144 (2015-10-09)
Combination chemotherapy is an effective strategy for increasing anticancer efficacy, reducing side effects and alleviating drug resistance. Here we report that combination of the recently identified novel chalcone derivative, chalcone-24 (Chal-24), and TNF-related apoptosis-inducing ligand (TRAIL) significantly increases cytotoxicity in
商品
LC-MS/MS method quantifies similar polar nucleotide activated sugars using Supel™ Carbon LC column for simultaneous analysis.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门