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Merck
CN

A0752

Sigma-Aldrich

腺苷 5'-二磷酸核糖 钠盐

≥93%

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别名:
ADPR, 腺苷二磷酸核糖
经验公式(希尔记法):
C15H23N5O14P2
CAS号:
分子量:
559.32
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

生物来源

yeast (candida utilis)

质量水平

检测方案

≥93%

形式

powder

储存温度

−20°C

SMILES字符串

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC(O)C(O)C(O)C=O)C(O)C3O

InChI

1S/C15H23N5O14P2.Na.H/c16-13-9-14(18-4-17-13)20(5-19-9)15-12(26)11(25)8(33-15)3-32-36(29,30)34-35(27,28)31-2-7(23)10(24)6(22)1-21;;/h1,4-8,10-12,15,22-26H,2-3H2,(H,27,28)(H,29,30)(H2,16,17,18);;

InChI key

NWPVXDZLQTURKI-UHFFFAOYSA-N

应用

使用5′-脱氧-5′-(甲硫基)腺苷:
  • 给出一系列烟酰胺腺嘌呤二核苷酸(NADH)
  • 氧化速率,用于呼吸链复合体(CI/CIII/CIV)
  • CI/替代(AOX) 通路
  • 测定聚腺苷二磷酸核糖甘油水解酶活性
  • 聚腺苷二磷酸核糖(PAR)结合竞争性分析
  • 氧化酶(AOX)通路
  • 测定聚腺苷二磷酸核糖甘油水解酶活性
  • 聚腺苷二磷酸核糖(PAR)结合竞争性分析

生化/生理作用

通过聚腺苷二磷酸核糖聚合酶(PARP)家族成员形成聚腺苷二磷酸核糖(ADP-ribose)时,腺苷5′-二磷酸核糖(ADP-Ribose)用作底物的基础嵌段。聚腺苷酸核糖的形成和降解是脱氧核糖核酸修复和凋亡信号的重要组成部分。ADP-核糖启动瞬时受体电位亚家族褪黑素 2 型 (TRPM2),即 Na+、Ca2+和K+阳离子通道。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

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LC-MS/MS method quantifies similar polar nucleotide activated sugars using Supel™ Carbon LC column for simultaneous analysis.

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