A0606
金硫代葡萄糖 水合物
≥96% (titration), PKCι-Par6 interaction inhibitor, powder
别名:
Solganal, Solganol, 金硫代葡萄糖
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关于此项目
经验公式（希尔记法）:
C6H11AuO5S · xH2O
化学文摘社编号:
分子量:
392.18 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
EC Number:
235-365-7
产品名称
金硫代葡萄糖 水合物, ≥96% (titration)
InChI
1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1
InChI key
SGVIEHTYEMEDRR-PKXGBZFFSA-M
SMILES string
O.OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O
assay
≥96% (titration)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 5 mg/mL, clear
storage temp.
2-8°C
Quality Level
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
P Huypens et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 38(8), 486-490 (2006-08-31)
Following the chemically-induced lesion of the ventromedial nucleus, gold-thioglucose treated rodents display hypothalamic leptin resistance, hyperphagia, hyperinsulinemia and obesity. Despite the exuberant hyperinsulinemia following gold-thioglucose treatment, systemic insulin sensitivity is preserved during the early phase of the obesity syndrome, resulting
Hiroshi Karasawa et al.
Obesity (Silver Spring, Md.), 19(3), 514-521 (2010-08-14)
An obesity-induced diabetes model using genetically normal mouse strains would be invaluable but remains to be established. One reason is that several normal mouse strains are resistant to high-fat diet-induced obesity. In the present study, we show the effectiveness of
Fumiko Isoda et al.
Brain research, 993(1-2), 172-176 (2003-12-04)
D-chiro-Inositol (DCI) enhances reproductive function in insulin-resistant women with polycystic ovarian disease and enhances the effects of insulin in the periphery, suggesting that this compound may act in part by sensitizing the hypothalamus to effects of insulin. Effects of gold-thioglucose
Kouichi Yoshinari et al.
Pharmaceutical research, 23(6), 1188-1200 (2006-05-23)
Changes in physiological, pathophysiological, and/or nutritional conditions often alter the expression of drug-metabolizing enzymes. In this study, we investigated obesity-induced changes in hepatic cytochrome P450 (P450) levels using nutritionally obese mice. To induce obesity, mice were fed a high-fat diet
Mitsunari Ogasawara et al.
Liver international : official journal of the International Association for the Study of the Liver, 31(4), 542-551 (2011-03-09)
The search for effective treatments of non-alcoholic steatohepatitis (NASH), now the most common chronic liver disease in affluent countries, is hindered by a lack of animal models having the range of anthropometric and pathophysiological features as human NASH. To examine
商品
Protein kinase C (PKC) is an AGC kinase that phosphorylates serine and threonine residues in many target proteins.
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