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Merck
CN

A0554

Sigma-Aldrich

4-乙酰氨基-4′-异硫氰酸芪-2,2′-磺酸二钠盐 二钠盐 水合物

powder, ≥80%

别名:

SITS, 二钠4-乙酰氨基-4′-异硫氰酸芪-2,2′-二磺酸

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About This Item

经验公式(希尔记法):
C17H12N2Na2O7S3 · xH2O
CAS号:
分子量:
498.46 (anhydrous basis)
Beilstein:
9177451
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

产品名称

4-乙酰氨基-4′-异硫氰酸芪-2,2′-磺酸二钠盐 二钠盐 水合物, ≥80%

质量水平

方案

≥80%

表单

powder

储存温度

−20°C

SMILES字符串

[Na+].[Na+].CC(=O)Nc1ccc(\C=C\c2ccc(cc2S([O-])(=O)=O)N=C=S)c(c1)S([O-])(=O)=O

InChI

1S/C17H14N2O7S3.2Na/c1-11(20)19-15-7-5-13(17(9-15)29(24,25)26)3-2-12-4-6-14(18-10-27)8-16(12)28(21,22)23;;/h2-9H,1H3,(H,19,20)(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b3-2+;;

InChI key

NPAWAMRXPHRVQY-WTVBWJGASA-L

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相关类别

应用

膜荧光标记;抑制膜的阴离子渗透性。通过共价修饰特定的 Lys 残基还可以使 Na、K-ATPase 失活。

其他说明

主要是反式异构体

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

M Montana Quick et al.
Journal of the American Society for Mass Spectrometry, 28(7), 1462-1472 (2017-03-21)
N-terminal derivatization of peptides with the chromogenic reagent 4-acetamido-4-isothiocyanatostilbene-2,2-disulfonic acid (SITS) is demonstrated to enhance the efficiency of 266 nm ultraviolet photodissociation (UVPD). Attachment of the chromophore results in a mass shift of 454 Da and provides significant gains in the number
C H Pedemonte et al.
FEBS letters, 314(1), 97-100 (1992-12-07)
The sodium pump or Na,K-ATPase, maintains the Na+ and K+ gradients across eukaryotic cell membranes at the expense of ATP. Incubation of purified canine renal Na,K-ATPase with 4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid (SITS) inhibited the ATPase activity. Both the labeling of the protein
Dennis Kolosov et al.
Insect biochemistry and molecular biology, 116, 103263-103263 (2019-11-05)
Malpighian tubules (MTs) and the hindgut together constitute the excretory system of insects. Larvae of lepidopterans (butterflies and moths) demonstrate the so-called cryptonephric arrangement, where the distal blind end of each MT is embedded into the rectal complex. The rest
Donglin Guo et al.
American journal of physiology. Heart and circulatory physiology, 295(1), H97-H104 (2008-04-29)
T-wave alternans, characterized by a beat-to-beat change in T-wave morphology, amplitude, and/or polarity on the ECG, often heralds the development of lethal ventricular arrhythmias in patients with left ventricular hypertrophy (LVH). The aim of our study was to examine the
Pedro Gonçalves et al.
Naunyn-Schmiedeberg's archives of pharmacology, 379(4), 325-336 (2008-11-22)
The aim of this study was to investigate the putative influence of some pharmacological agents and drugs of abuse upon the apical uptake of butyrate (BT) into Caco-2 cells. The apical uptake of (14)C-BT by Caco-2 cells was (1) time

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