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Merck
CN
所有图片(1)

文件

A0232

Sigma-Aldrich

盐酸阿夫唑嗪 盐酸盐

≥98% (HPLC), solid

别名:

N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride, Uroxatral hydrochloride

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About This Item

经验公式（希尔记法）:
C19H27N5O4 · HCl
CAS号:
81403-68-1
分子量:
425.91
MDL编号:
MFCD00879135
UNSPSC代码:
12352200
PubChem化学物质编号:
329770590
NACRES:
NA.77

质量水平

100

检测方案

≥98% (HPLC)

形式

solid

储存条件

desiccated

溶解性

DMSO: >10 mg/mL
H2O: insoluble

创始人

Sanofi Aventis

SMILES字符串

Cl.COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C3CCCO3

InChI

1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H

InChI key

YTNKWDJILNVLGX-UHFFFAOYSA-N

基因信息

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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生化/生理作用

Alfuzosin hydrochloride is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.

特点和优势

This compound is featured on the α1-Adrenoceptors and α2-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Jarosław Szulfer et al.
Journal of chromatography. A, 1346, 69-77 (2014-05-06)
This paper focuses on the application of a column classification system based on the Katholieke Universiteit Leuven for the characterization of physicochemical properties of core-shell and ultra-high performance liquid chromatographic stationary phases, followed by the verification of the reliability of
Satyanarayan Pattnaik et al.
Medicina (Kaunas, Lithuania), 51(4), 253-261 (2015-10-02)
There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement. A principal physicochemical factor which controls the passive diffusion of a solute from a vehicle into the skin arises

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