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Merck
CN

A7009

氨基胍 半硫酸盐

≥98%

别名:

甲脒肼 半硫酸盐

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关于此项目

线性分子式:
CH6N4 · 1/2H2SO4
化学文摘社编号:
分子量:
123.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
213-628-7
MDL number:
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产品名称

氨基胍 半硫酸盐, ≥98%

InChI key

VKGQPUZNCZPZKI-UHFFFAOYSA-N

InChI

1S/2CH6N4.H2O4S/c2*2-1(3)5-4;1-5(2,3)4/h2*4H2,(H4,2,3,5);(H2,1,2,3,4)

SMILES string

NNC(N)=N.NNC(N)=N.OS(O)(=O)=O

biological source

synthetic (organic)

assay

≥98%

form

powder

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless

storage temp.

room temp

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Application

氨基胍可抑制组成型和诱导型一氧化氮合成酶。氨基胍也被用于研究一氧化氮对排卵和卵巢类固醇生成和前列腺素产生的影响。

Biochem/physiol Actions

构成型和诱导型一氧化氮合酶两者都抑制

Features and Benefits

该化合物在受体分类和信号转导手册的一氧化氮合酶页面上有重点介绍。想要浏览手册的其他页面, 请单击此处

存储类别

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jong Jin Park et al.
Food chemistry, 338, 128150-128150 (2020-10-24)
This study aimed to develop efficient adsorption and desorption processes to purify phenolic compounds from Ecklonia cava. We compared the adsorption and desorption properties of five resins. HP2MG showed the highest adsorption and desorption capacities and adsorption rate; hence, it
Fernanda Hansen et al.
Amino acids, 48(2), 375-385 (2015-09-09)
Diabetes is a metabolic disease characterized by high fasting-glucose levels. Diabetic complications have been associated with hyperglycemia and high levels of reactive compounds, such as methylglyoxal (MG) and advanced glycation endproducts (AGEs) formation derived from glucose. Diabetic patients have a
Caroline Zanotto et al.
Molecular neurobiology, 56(5), 3538-3551 (2018-08-27)
Diabetes mellitus is a metabolic disorder that results in glucotoxicity and the formation of advanced glycated end products (AGEs), which mediate several systemic adverse effects, particularly in the brain tissue. Alterations in glutamatergic neurotransmission and cognitive impairment have been reported
J Yamauchi et al.
Endocrinology, 138(9), 3630-3637 (1997-09-01)
Evidence supports the involvement of nitric oxide (NO) in ovarian physiology. The present study was undertaken to investigate the role of the NO/NO synthase (NOS) systems in ovulation, oocyte maturation, ovarian steroidogenesis, and PG production using in vitro perfused rabbit
Wei Chen et al.
Oxidative medicine and cellular longevity, 2022, 8854457-8854457 (2022-01-18)
Cerebral endothelial cells play an essential role in brain angiogenesis, and their function has been found to be impaired in diabetes. Methylglyoxal (MG) is a highly reactive dicarbonyl metabolite of glucose formed mainly during glycolysis, and its levels can be

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Cellular oxidative stress is countered by enzymatic scavengers and antioxidant modulators against reactive oxygen species damage.

氧化应激,在一部分上,是由多种细胞过程产生的活性氧介导,并由诸如酶清除剂或抗氧化剂调节剂等细胞抗氧化剂机制所控制的。自由基,如活性氧,会通过细胞引起细胞损伤。

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