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A3773

4-四氢吖啶盐酸盐水合物

Name: 4-四氢吖啶 盐酸盐 水合物
Brand: SIGMA
Price: 4489.38 CNY
Availability: InStock

≥99%

别名:

THA 盐酸盐水合物, Tacrine hydrochloride, 单满吖啶氨盐酸盐水合物

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250 μG

CN¥4,489.38

预计发货时间May 16, 2025详情

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250 μG

CN¥4,489.38

About This Item

经验公式（希尔记法）:

C₁₃H₁₄N₂ · HCl · xH₂O

CAS号:

206658-92-6

分子量:

234.72 (anhydrous basis)

MDL编号:

MFCD00150067

UNSPSC代码:

51111800

PubChem化学物质编号:

24278139

NACRES:

NA.77

CN¥4,489.38

预计发货时间May 16, 2025详情

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此商品	A9511	A4327	A8301
A1653 Albumin from human serum	A9511 Albumin from human serum	A4327 Albumin from human serum	A8301 Albumin, glycated human
assay ≥96% (agarose gel electrophoresis)	assay ≥97% (agarose gel electrophoresis)	assay ≥96% (agarose gel electrophoresis)	assay 90-100% protein basis (biuret)
biological source human	biological source human	biological source human	biological source human
technique(s) ELISA: suitable, western blot: suitable, tissue culture: suitable	technique(s) ELISA: suitable, tissue culture: suitable, western blot: suitable	technique(s) tissue culture: suitable	technique(s) cell culture \| mammalian: suitable
Quality Level 300	Quality Level 300	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
impurities HIV I and HIVII, HCV and HBsAg, tested negative	impurities HIV I and HIVII, HCV and HBsAg, tested negative	impurities HIV I and HIVII, HCV and HBsAg, tested negative	impurities -

特点和优势

该化合物是受体分类及信号转导手册上乙酰胆碱合成代谢和组胺合成代谢页面上的推荐化合物。想要浏览手册的其他页面，请单击此处。

象形图

GHS06,GHS08

警示用语：

Danger

危险声明

H301 + H311 + H331,H315,H319,H335,H351

预防措施声明

P202 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338

危险分类

Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

M Harel et al.

Proceedings of the National Academy of Sciences of the United States of America, 90(19), 9031-9035 (1993-10-01)

Binding sites of Torpedo acetylcholinesterase (EC 3.1.1.7) for quaternary ligands were investigated by x-ray crystallography and photoaffinity labeling. Crystal structures of complexes with ligands were determined at 2.8-A resolution. In a complex with edrophonium, and quaternary nitrogen of the ligand

Effects of cabergoline and rotigotine on tacrine-induced tremulous jaw movements in rats.

Go Koganemaru et al.

Pharmacology, biochemistry, and behavior, 126, 103-108 (2014-09-30)

We examined the effects of two dopamine agonists, cabergoline and rotigotine, on tacrine-induced tremor and c-Fos expression in rats. Rats received intraperitoneal injection of cabergoline (0.5, 1.0, or 5.0mg/kg), rotigotine (1.0, 2.5, or 10.0mg/kg), or vehicle 30min before intraperitoneal injection

Combined Pre- and Posttreatment of Paraoxon Exposure.

Dietrich E Lorke et al.

Molecules (Basel, Switzerland), 25(7) (2020-04-02)

Organophosphates (OPCs), useful agents as pesticides, also represent a serious health hazard. Standard therapy with atropine and established oxime-type enzyme reactivators is unsatisfactory. Experimental data indicate that superior therapeutic results can be obtained when reversible cholinesterase inhibitors are administered before

Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease.

Jinggong Liu et al.

Biochimica et biophysica acta, 1840(9), 2886-2903 (2014-05-14)

Alzheimer's disease (AD) is a progressive neurodegenerative brain disorder that is characterized by dementia, cognitive impairment, and memory loss. Diverse factors are related to the development of AD, such as increased level of β-amyloid (Aβ), acetylcholine, metal ion deregulation, hyperphosphorylated

Structure-Based Scaffold Repurposing toward the Discovery of Novel Cholinesterase Inhibitors.

Satish N Dighe et al.

ACS omega, 5(48), 30971-30979 (2020-12-17)

Cholinesterases (ChE) are well-known drug targets for the treatment of Alzheimer's disease (AD). In continuation of work to develop novel cholinesterase inhibitors, we utilized a structure-based scaffold repurposing approach and discovered six novel ChE inhibitors from our recently developed DNA

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4-四氢吖啶盐酸盐水合物

≥99%

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