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Merck
CN

96329

Kollicoat® SR 30 D

28.5-31.5% solids basis

别名:

Poly(vinyl acetate) dispersion 30 %, Poly(vinyl acetate) stabilized with polyvinylpyrrolidone and sodium lauryl sulfate

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化学文摘社编号:
UNSPSC Code:
12162002
NACRES:
NA.25
MDL number:
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产品名称

Kollicoat® SR 30 D, 28.5-31.5% solids basis

SMILES string

O(C(=O)C)C=C

InChI

1S/C4H6O2/c1-3-6-4(2)5/h3H,1H2,2H3

InChI key

XTXRWKRVRITETP-UHFFFAOYSA-N

assay

25.0-30.0% (saponification value * 0.1534)
28.5-31.5% solids basis

form

dispersion

impurities

≤0.5% sulfated ash (verified on random samples only)
≤0.500% particulate matter, agglomerates
≤100 ppm residual monomer vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals (verified on random samples only)
≤4.0% povidone (N content/0.126)

pH

3.0-5.5

viscosity

≤100 mPa.s(20 °C, Brookfield RVT) (SP. 1, 100 PRM)

density

1.045-1.065

Quality Level

Analysis Note

appearance and solubility of a film must conform

Application

Kollicoat SR is use as a controlled-release coating or as a matrix. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.

Legal Information

Kollicoat is a registered trademark of BASF SE

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sandra Strübing et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 708-717 (2008-02-06)
The purpose of this study was to investigate the mechanism of floating and drug release behaviour of poly(vinyl acetate)-based floating tablets with membrane controlled drug delivery. Propranolol HCl containing tablets with Kollidon SR as an excipient for direct compression and
Wiesław Sawicki et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 60(1), 153-158 (2005-04-26)
The purpose of this study was to work out a method of compression of floating pellets with verapamil hydrochloride (VH) in a dose of 40 mg. It was assumed that this form should reside in the stomach floating for several
Nizar Al-Zoubi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 735-742 (2008-02-23)
Sustained-release of buspirone HCl (BUH) was attempted by spray drying after dissolving in two commercially available aqueous polymeric dispersions (Eudragit RS 30 D or Kollicoat SR 30 D) at five different drug:polymer ratios (1:1, 1:2, 1:3, 1:6 and 1:9). The
Vibha Puri et al.
Journal of pharmaceutical sciences, 101(1), 342-353 (2011-09-22)
Amorphous solid dispersions (ASDs) may entail tailor-made dosage form design to exploit their solubility advantage. Surface phenomena dominated the performance of amorphous celecoxib solid dispersion (ACSD) comprising of amorphous celecoxib (A-CLB), polyvinylpyrrolidone, and meglumine (7:2:1, w/w). ACSD cohesive interfacial interactions
V Andonova et al.
Die Pharmazie, 67(7), 601-604 (2012-08-15)
During the last decade the number of investigations on the preparation and application of more effective drug release systems on the basis of nanocarriers from biocompatible and biodegradable polymers are considerably increasing. This is notably in force for practically water

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