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质量水平
方案
25.0-30.0% (saponification value * 0.1534)
28.5-31.5% solids basis
表单
dispersion
杂质
≤0.5% sulfated ash (verified on random samples only)
≤0.500% particulate matter, agglomerates
≤100 ppm residual monomer vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals (verified on random samples only)
≤4.0% povidone (N content/0.126)
pH值（酸碱度）
3.0-5.5
粘度
≤100 mPa.s(20 °C, Brookfield RVT) (SP. 1, 100 PRM)
密度
1.045-1.065
SMILES字符串
O(C(=O)C)C=C
InChI
1S/C4H6O2/c1-3-6-4(2)5/h3H,1H2,2H3
InChI key
XTXRWKRVRITETP-UHFFFAOYSA-N
应用
Kollicoat SR is use as a controlled-release coating or as a matrix. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
分析说明
appearance and solubility of a film must conform
法律信息
Kollicoat is a registered trademark of BASF SE
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Sandra Strübing et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 708-717 (2008-02-06)
The purpose of this study was to investigate the mechanism of floating and drug release behaviour of poly(vinyl acetate)-based floating tablets with membrane controlled drug delivery. Propranolol HCl containing tablets with Kollidon SR as an excipient for direct compression and
Wiesław Sawicki et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 60(1), 153-158 (2005-04-26)
The purpose of this study was to work out a method of compression of floating pellets with verapamil hydrochloride (VH) in a dose of 40 mg. It was assumed that this form should reside in the stomach floating for several
Nizar Al-Zoubi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 735-742 (2008-02-23)
Sustained-release of buspirone HCl (BUH) was attempted by spray drying after dissolving in two commercially available aqueous polymeric dispersions (Eudragit RS 30 D or Kollicoat SR 30 D) at five different drug:polymer ratios (1:1, 1:2, 1:3, 1:6 and 1:9). The
Zsombor K Nagy et al.
Journal of pharmaceutical sciences, 101(1), 322-332 (2011-09-16)
Electrospinning (ES) and extrusion of a poorly water-soluble active pharmaceutical ingredient were used to improve its dissolution, which is a major challenge in the field of pharmaceutical technology. Spironolactone was applied as model drug and recently developed polyvinyl caprolactame-polyvinyl acetate-polyethylene
Ehab A Fouad et al.
Expert opinion on drug delivery, 8(5), 693-703 (2011-03-23)
Developments in industrial pharmacy are often linked to the discovery of pharmaceutical excipients. Although recently introduced as a material for immediate release coatings, Kollicoat IR already has other applications. In this review, the different properties and pharmaceutical applications of Kollicoat
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