推荐产品
质量水平
产品线
BioUltra
形式
powder or crystals (or flakes)
分子量
Mr ~35000
杂质
insoluble matter:, passes filter test
≤0.005% peroxides (as H2O2):
pH值（酸碱度）
5.5-7.0 (25 °C, 50 mg/mL in H2O)
mp
64-66 °C
溶解性
H2O: 50 mg/mL at 25 °C, clear, colorless
痕量阴离子
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg
痕量阳离子
Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg
λ
50 mg/mL in H2O
紫外吸收
λ: 260 nm Amax: 0.12
λ: 280 nm Amax: 0.12
SMILES字符串
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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一般描述
聚乙二醇(PEG)是一种聚醚化合物，用于作为化妆品，药品及食品的添加剂。它包含重复的乙二醇[-(CH2CH2O)n]单元。
应用
聚乙二醇被用于:
- 作为威斯康星大学(UW)冷藏溶液的组分，在温度变化期间稳定肝细胞的细胞膜
- 作为过冷液的组分，研究大鼠移植肝脏的过冷保存技术，防止低温损伤
- 制备用于制造多细胞球体(MCS)培养物的水相
生化/生理作用
聚乙二醇(PEG)是一种合成高分子，被用作生物偶联和纳米药物延长血液循环时间，提高药物疗效的金标准。它通过防止冰结晶来充当冰调节剂，这对细胞膜是有益的。PEG可防止细胞低温损伤，如脂质过氧化和细胞膜损伤。PEG-偶联药物被认为可在人体上安全使用，并得到美国食品和药品监督局（FDA）批准。PEG在许多生物医学应用，包括生物传感器，成像和组织工程。它还排斥蛋白质吸附和降低肝脏摄取，这有助于包裹纳米颗粒。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Wontae Lee et al.
Nature communications, 10(1), 144-144 (2019-01-13)
Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, we develop ultrasoft mechanosensors that visibly deform under less than 10 Pascals of cell-generated stress. By incorporating these mechanosensors into multicellular spheroids
Bote G Bruinsma et al.
Nature protocols, 10(3), 484-494 (2015-02-19)
The current standard for liver preservation involves cooling of the organ on ice (0-4 °C). Although it is successful for shorter durations, this method of preservation does not allow long-term storage of the liver. The gradual loss of hepatic viability
Janina-Miriam Noy et al.
Biomacromolecules, 21(6), 2320-2333 (2020-04-29)
Phosphorylcholine is known to repel the absorption of proteins onto surfaces, which can prevent the formation of a protein corona on the surface of nanoparticles. This can influence the fate of nanoparticles used for drug delivery. This material could therefore
Anisha A D'souza et al.
Expert opinion on drug delivery, 13(9), 1257-1275 (2016-04-28)
Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development. The unique
Thai Thanh Hoang Thi et al.
Polymers, 12(2) (2020-02-07)
Poly(ethylene glycol) (PEG) is widely used as a gold standard in bioconjugation and nanomedicine to prolong blood circulation time and improve drug efficacy. The conjugation of PEG to proteins, peptides, oligonucleotides (DNA, small interfering RNA (siRNA), microRNA (miRNA)) and nanoparticles
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