推荐产品
生物来源
Lonicera japonica
质量水平
检测方案
≥98.0% (HPLC)
形式
powder or crystals
缺失
≤3.0% loss on drying
应用
metabolomics
vitamins, nutraceuticals, and natural products
SMILES字符串
O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H]1O)C(O)=O
InChI
1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14+,16-/m1/s1
InChI key
CWVRJTMFETXNAD-NXLLHMKUSA-N
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一般描述
新绿原酸是咖啡酸和奎宁酸的酯类多酚化合物。它是绿原酸的异构体。
应用
新绿原酸已被用于：
- 采用高效液相色谱(HPLC)技术测定半齿锯根和地上部分酚类物质的含量
- 研究梅干对人滑膜成纤维细胞(hSF)的抗炎反应和类风湿性关节炎转基因小鼠的骨吸收
- 用于绿咖啡豆提取物对人肝癌细胞株(HepG2)的定量和毒性分析
生化/生理作用
新绿原酸对黑色素的生物合成有抑制作用。因此可用于已收割的果实，防止松念珠菌引起的褐腐病侵染。它还显示了令人印象深刻的抗氧化、抗菌、抗病毒和解热特性。由于新绿原酸具有抗炎活性，在急性和慢性炎症的治疗中具有潜在的应用价值。由于在乳腺癌细胞系MDA-MB-435中发现了生长抑制作用，它可能作为化学预防化合物发挥作用。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
PHENOLIC COMPOUNDS OF SERRATULA CENTAUROIDES AND ANXIOLYTIC EFFECT
NIKOLAEVA G
Farmacia, 67(3), 504-510 (2019)
Faryal Mirza et al.
The Journal of nutritional biochemistry, 52, 54-61 (2017-11-18)
Dried plum (DP), a rich source of polyphenols has been shown to have bone-preserving properties in both animal models of osteoporosis and postmenopausal women. We evaluated if DP alleviated the destruction of joints in transgenic mice (TG) that overexpress human
Yanjuan Wang et al.
Biomedical chromatography : BMC, 29(1), 68-74 (2014-05-21)
A simple, specific and sensitive ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was established and validated for simultaneous determination of neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid and geniposide in rat plasma using puerarin as an internal standard (IS). Plasma
Chao-Mei Ma et al.
Bioorganic & medicinal chemistry, 18(2), 863-869 (2009-12-17)
In our continued research on chlorogenic acid analogues and derivatives with improved bioactivity, we have synthesized some caffeoyl 5,6-anhydroquinic acid derivatives. The 1,7 acetonides of chlorogenic acid (15), and of the mono-caffeoyl 5,6-anhydroquinic acids (7-8) showed appreciable anti-HIV activity. The
Maria Villarino et al.
Journal of agricultural and food chemistry, 59(7), 3205-3213 (2011-03-05)
Chlorogenic acid (CGA) and its isomer, neochlorogenic acid (NCGA), were found to be the major phenolic compounds in the flesh and peel of three peach cultivars. Their concentrations are especially high in immature fruits (CGA, 151-548 mg/kg; NCGA, 85-380 mg/kg)
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