94335
尿苷5′-二磷酸葡萄糖 二钠盐
≥98.0% (HPLC), from Saccharomyces cerevisiae, powder
别名:
UDP-D-葡萄糖二钠盐, UDPG, UDP-glc, 尿苷[5’]二磷酸[1]-α-D-吡喃葡萄糖 二钠盐, 尿苷二磷酸葡萄糖 二钠盐
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关于此项目
经验公式（希尔记法）:
C15H22N2Na2O17P2
化学文摘社编号:
分子量:
610.27
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
248-801-6
MDL number:
Beilstein/REAXYS Number:
4290380
产品名称
尿苷5′-二磷酸葡萄糖 二钠盐, ≥98.0% (HPLC)
InChI
1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1
InChI key
PKJQEQVCYGYYMM-QBNUFUENSA-L
SMILES string
[Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O
biological source
Saccharomyces cerevisiae
assay
≥98.0% (HPLC)
form
powder
impurities
≤5% solvent
≤8.5% water
solubility
H2O: 50 mg/mL, clear
storage temp.
−20°C
Other Notes
促进甲烷杆菌无细胞提取液中甲基辅酶 M 的降解
Application
UDP-葡萄糖已用于：
- 作为糖苷化合物的酶促生产底物，并用于它们的液相色谱-质谱检测。
- 作为底物用于人CMP-Sia转运蛋白的底物筛选和吸附亲和力测定。
Biochem/physiol Actions
UDP-葡萄糖是UDP-半乳糖和UDP-葡糖醛酸的前体。在动物和某些微生物中，它还用于含葡萄糖分子的生物合成，例如寡糖、多糖、糖蛋白和糖脂。多个研究表明，除了经典的代谢作用外，UDP-葡萄糖可能是植物中的信号分子。5′二磷酸尿苷葡萄糖可作为激动剂作用于G蛋白偶联受体(GPCR)嘌呤受体P2Y14，参与树突状细胞和胶质细胞的激活。也可通过激活G蛋白偶联受体17(GPR17)诱导少突胶质细胞分化。
General description
5′-二磷酸尿苷葡萄糖二钠盐是由尿嘧啶碱基、核糖和2个磷酸基团组成的核苷酸糖。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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