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Merck
CN

94261

LL-37 (human) trifluoroacetate salt

≥95% (HPLC)

别名:

Human LL-37 amide Trifluoroacetate

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关于此项目

经验公式(希尔记法):
C205H341N61O52 · xC2HF3O2
分子量:
4492.28 (free base basis)
NACRES:
NA.85
UNSPSC Code:
51101500
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产品名称

LL-37 (human) trifluoroacetate salt, ≥95% (HPLC)

assay

≥95% (HPLC)

form

powder (Lyophilisate)

color

colorless to white

solubility

H2O: 1 mg/mL, clear, colorless

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
viruses

mode of action

cell membrane | interferes

storage temp.

−20°C

Quality Level

Application

LL-37 is used to study host defense mechanisms.

Biochem/physiol Actions

LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria.

General description

Chemical structure: peptide

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.

Packaging

1mg

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ainhoa Revilla-Guarinos et al.
Applied and environmental microbiology, 86(14) (2020-05-18)
Bce-like systems mediate resistance against antimicrobial peptides in Firmicutes bacteria. Lactobacillus casei BL23 encodes an "orphan" ABC transporter that, based on homology to BceAB-like systems, was proposed to contribute to antimicrobial peptide resistance. A mutant lacking the permease subunit was

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