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Merck
CN

94121

Sigma-Aldrich

黄芩苷

≥99.0% (HPLC)

别名:

5,6-二羟基-4-氧代-2-苯基-4 H -1-苯并吡喃-7-基-β-D-吡喃葡萄糖醛酸, 黄芩素 7- O -β- D -葡糖苷酸

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About This Item

经验公式(希尔记法):
C21H18O11
CAS号:
分子量:
446.36
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:

生物来源

synthetic

方案

≥99.0% (HPLC)

表单

solid

旋光性

[α]/D -83±3°, c = 1 in DMSO

技术

HPLC: suitable

mp

202-205 °C (dec.) (lit.)

SMILES字符串

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccccc4

InChI

1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1

InChI key

IKIIZLYTISPENI-ZFORQUDYSA-N

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应用

Baicalin, a flavonoid compound with potential therapeutic value, is used to study its anti-inflammatory and anti-oxidant properties. Baicalin is also used to study its potential as an anti-sepsis agent.

生化/生理作用

Baicalin, a component of Traditional Chinese Medicine (TCM), is a flavonoid component found in several species in the genus Scutellaria. Baicalin is an inhibitor of prolyl endopeptidases.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Z Gao et al.
Biochimica et biophysica acta, 1472(3), 643-650 (1999-11-24)
Free radical scavenging and antioxidant activities of baicalein, baicalin, wogonin and wogonoside, the four major flavonoids in the radix of Scutellaria baicalensis Georgi, were examined in different systems. ESR results showed that baicalein and baicalin scavenged hydroxyl radical, DPPH radical
Zhenhua Pei et al.
Journal of periodontology, 85(9), 1283-1290 (2014-01-31)
Periodontitis is the most common cause of tooth loss in adults. Periodontal ligament cell (PLC)-based therapy is considered one of the most promising methods in periodontal tissue regeneration. The traditional Chinese medicine baicalin has been shown to possess antimicrobial and
Xi-Ping Zhang et al.
World journal of gastroenterology, 13(38), 5079-5089 (2007-09-19)
To investigate the protective effects and mechanisms of Baicalin and octreotide on renal injury of rats with severe acute pancreatitis (SAP). One hundred and eighty SD rats were randomly assigned to the model group, Baicalin-treated group, octreotide-treated group and sham
Miao Lin et al.
BMC complementary and alternative medicine, 14, 19-19 (2014-01-15)
Renal ischemia-reperfusion injury (IRI) increases the rates of acute kidney failure, delayed graft function, and early mortality after kidney transplantation. The pathophysiology involved includes oxidative stress, mitochondrial dysfunction, and immune-mediated injury. The anti-oxidation, anti-apoptosis, and anti-inflammation properties of baicalin, a
T B Ng et al.
Life sciences, 66(8), 709-723 (2000-02-19)
A variety of flavonoids, lignans, an alkaloid, a bisbenzyl, coumarins and terpenes isolated from Chinese herbs was tested for antioxidant activity as reflected in the ability to inhibit lipid peroxidation in rat brain and kidney homogenates and rat erythrocyte hemolysis.

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