产品名称
DL -2,6-二氨基庚二酸, ≥95% (TLC)
SMILES string
OC([C@@H](N)CCC[C@H](N)C(O)=O)=O
InChI key
GMKMEZVLHJARHF-WHFBIAKZSA-N
InChI
1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1
assay
≥95% (TLC)
form
powder
Quality Level
Application
DL-2,6-二氨基庚二酸是中消旋DAP的立体异构体,可用作用于鉴定反刍动物瘤胃中细菌和真菌标记物的测定的参考材料。
Analysis Note
非对映纯度 ≥98.0% (HPLC)
Biochem/physiol Actions
内消旋DAP的立体异构体。meso-DAP是许多细菌细胞壁中必需氨基酸L-赖氨酸和肽聚糖成分的生物合成前体。由于在哺乳动物生物化学中未观察到这些功能,因此α,α′-二氨基二酸(DAD)作为具有低哺乳动物毒性的潜在抗生素而受到关注。
Packaging
无底玻璃瓶。内含物装在锥底内插管中。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
The DAP pathway to lysine as a target for antimicrobial agents.
R J Cox
Natural product reports, 13(1), 29-43 (1996-02-01)
Yea Hwang Moon et al.
Animal science journal = Nihon chikusan Gakkaiho, 81(6), 642-647 (2010-11-27)
A comparative study among Korean native cow (Hanwoo), Holstein dairy cow, Korean native goat and crossbred sheep on the population and marker concentration of ruminal microbes, the activities of carboxymethylcellulase (CMCase), xylanase and amylase, and in situ dry matter (DM)
Zhaoxian Xu et al.
Scientific reports, 5, 17400-17400 (2015-12-04)
Poly(L-diaminopropionic acid) (PDAP) is one of the four homopoly(amino acid)s that have been discovered in nature. However, the molecular mechanism of PDAP biosynthesis has yet to be described. In this work, the general layout of the PDAP biosynthetic pathway is
Diaminopimelate and lysine.
Patte, J. C.
Amino Acids: Biosynthesis and Genetic Regulation, 3, 213-228 (1983)
A Day et al.
The Biochemical journal, 161(3), 677-685 (1977-03-01)
An enzymic assay for individual isomers (meso-, LL- and DD-) of 2,6-diaminopimelate was developed. The enzyme 2,6-diaminopimelate decarboxylase specifically attacked meso-diaminopimelate and was used to measure this isomer manometrically. The meso- and LL-isomers were measured together manometrically in a coupled
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